中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
机构
采集方式
内容类型
发表日期
学科主题
筛选

浏览/检索结果: 共10条,第1-10条 帮助

条数/页: 排序方式:
Potency Prediction of Covalent Inhibitors against SARS-CoV-2 3CL-like Protease and Multiple Mutants by Multiscale Simulations 期刊论文  OAI收割
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2024, 卷号: 64, 期号: 24, 页码: 9501-9516
作者:  
Xiong, Muya;  Nie, Tianqing;  Li, Zhewen;  Hu, Meiyi;  Su, Haixia
  |  收藏  |  浏览/下载:4/0  |  提交时间:2025/01/06
Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein Inhibitors 期刊论文  OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 页码: 14
作者:  
Wang, Xudong;  Xiong, Liwei;  Zhu, Ying;  Liu, Sixiu;  Zhao, Wenfeng
  |  收藏  |  浏览/下载:6/0  |  提交时间:2024/12/25
Chemical Space Profiling of SARS-CoV-2 PLpro Using DNA-Encoded Focused Libraries 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 10
作者:  
Wang, Xudong;  Zhu, Ying;  Zhao, Qingyi;  Lu, Weiwei;  Xu, Yechun
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/05/07
Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:  
Wen, Xin;  Zhang, Minmin;  Duan, Zhiqiang;  Suo, Yanrui;  Lu, Weiwei
  |  收藏  |  浏览/下载:47/0  |  提交时间:2023/10/17
Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease 期刊论文  OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 15
作者:  
Wang, Qian;  Chen, Guofeng;  He, Jian;  Li, Jiameng;  Xiong, Muya
  |  收藏  |  浏览/下载:33/0  |  提交时间:2023/10/17
Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches 期刊论文  OAI收割
CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 18, 页码: 4681-4696
作者:  
Shao, Qiang;  Xiong, Muya;  Li, Jiameng;  Hu, Hangchen;  Su, Haixia
  |  收藏  |  浏览/下载:6/0  |  提交时间:2024/03/27
Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 10
作者:  
Hu, Hangchen;  Wang, Qian;  Su, Haixia;  Shao, Qiang;  Zhao, Wenfeng
  |  收藏  |  浏览/下载:25/0  |  提交时间:2023/04/10
Structure-based design of a novel inhibitor of the ZIKA virus NS2B/ NS3 protease 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 7
作者:  
Xiong, Yanchao;  Cheng, Fei;  Zhang, Junyi;  Su, Haixia;  Hu, Hangchen
  |  收藏  |  浏览/下载:37/0  |  提交时间:2022/11/11
Identification of Highly Selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors by a Covalent Fragment-Based Approach 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 13, 页码: 7052-7065
作者:  
Huang, Fubao;  Hu, Hangchen;  Wang, Kai;  Peng, Chengyuan;  Xu, Wenwei
  |  收藏  |  浏览/下载:66/0  |  提交时间:2020/12/24
Structure-Based Survey of the Binding Modes of BACE1 Inhibitors 期刊论文  OAI收割
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 2, 页码: 880-889
作者:  
Hu, Hangchen;  Chen, Zhaoqiang;  Xu, Xiang;  Xuo, Yechun
  |  收藏  |  浏览/下载:19/0  |  提交时间:2020/07/01