中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
海洋研究所 [3]
化学研究所 [1]
水生生物研究所 [1]
武汉病毒研究所 [1]
中国科学院大学 [1]
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OAI收割 [19]
iSwitch采集 [2]
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期刊论文 [21]
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2024 [1]
2023 [6]
2022 [3]
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Virology [2]
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Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2
期刊论文
OAI收割
STEROIDS, 2024, 卷号: 202, 页码: 8
作者:
Liu, Yaowen
;
Nie, Tianqing
;
Hou, Jinjun
;
Long, Huali
;
Zhang, Zijia
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/13
3CLpro
SARS-CoV-2
Betulinic acid
Natural product
Inhibitory activity
Deubiquitylating Enzymes in Cancer and Immunity
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 37
作者:
Ren, Jiang
;
Yu, Peng
;
Liu, Sijia
;
Li, Ran
;
Niu, Xin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
cancer
deubiquitylating enzymes (DUBs)
immunity
therapeutic approach
Preparation and characterization of nanobodies targeting SARS-CoV-2 papain-like protease
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106267
作者:
Qiao, Huarui
;
Li, Lingyun
;
Wang, Lu
;
Yu, Haijun
;
Hu, Fangzheng
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
SARS-CoV-2
Papain like protease (PLpro)
Nanobody
PLpro inhibitor
Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 15
作者:
Wang, Qian
;
Chen, Guofeng
;
He, Jian
;
Li, Jiameng
;
Xiong, Muya
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
SARS-CoV-2
papain-like protease
covalent inhibitor
co-crystal structure
in vitro assay
Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches
期刊论文
OAI收割
CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 18, 页码: 4681-4696
作者:
Shao, Qiang
;
Xiong, Muya
;
Li, Jiameng
;
Hu, Hangchen
;
Su, Haixia
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors
期刊论文
OAI收割
PROTEIN & CELL, 2023, 卷号: 14, 期号: 1, 页码: 17-27
作者:
Zang, Yi
;
Su, Mingbo
;
Wang, Qingxing
;
Cheng, Xi
;
Zhang, Wenru
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
high-throughput screening
SARS
CoV-2
main
papain-like
proteases
Flavonoids from the roots and rhizomes of Sophora tonkinensis and their in vitro anti-SARS-CoV-2 activity
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 1, 页码: 65
作者:
Li Zhuo
;
Xie Hang
;
Tang Chunping
;
Feng Lu
;
Ke Changqiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/05/22
Sophora tonkinensis
Flavonoid
Anti-SARS-CoV-2 activity
SARS-CoV-2 3CLpro
SARS-CoV-2 PLpro
Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 10
作者:
Hu, Hangchen
;
Wang, Qian
;
Su, Haixia
;
Shao, Qiang
;
Zhao, Wenfeng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/04/10
Allosteric Modulator
Cysteine 270
Drug Design
Papain-Like Protease
SARS-CoV-2
Parthenolide reveals an allosteric mode to inhibit the deISGylation activity of SARS-CoV-2 papain-like protease
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2022, 卷号: 54, 期号: 8, 页码: 1133-1139
作者:
Zou, Zhihui
;
Shan, Huizhuang
;
Sun, Demeng
;
Xia, Li
;
Shi, Yulong
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/11/11
COVID-19
SARS-CoV-2
PLpro
Parthenolide
deISGylation
Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2022, 卷号: 298, 期号: 8, 页码: 13
作者:
Cheong, Ezekiel Ze Ken
;
Quek, Jun Ping
;
Xin, Liu
;
Li, Chaoqiang
;
Chan, Jing Yi
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10