中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [68]
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期刊论文 [422]
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Molecular phylogenetic relationships based on mitochondrial genomes of novel deep-sea corals (Octocorallia: Alcyonacea): Insights into slow evolution and adaptation to extreme deep-sea environments
期刊论文
OAI收割
ZOOLOGICAL RESEARCH, 2024, 卷号: 45, 期号: 1, 页码: 215-225
作者:
Wei, Zhan-Fei
;
Ta, Kai-Wen
;
Zhang, Nan-Nan
;
Liu, Shan-Shan
;
Meng, Liang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/04/03
Mitochondrial genome
Alcyonacea
Ka/Ks evolution
Environmental factors
Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10
作者:
Chen, Guofeng
;
Xie, Hang
;
Liu, Jiayuan
;
Shao, Qiang
;
Li, Minjun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Methyl substitution
Selectivity
FABP4 inhibitor
Anti-inflammation
Metabolic stability
Differential response of Hg-methylating and MeHg-demethylating microbiomes to dissolved organic matter components in eutrophic lake water
期刊论文
OAI收割
Journal of Hazardous Materials, 2024, 卷号: 465, 页码: 133298
作者:
Zhengyu Wu
;
Zhike Li
;
Bo Shao
;
Ji Chen
;
Xiaomei Cui
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/14
Ecosystem responses dominate the trends of annual gross primary productivity over terrestrial ecosystems of China during 2000-2020
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2023, 卷号: 343, 页码: 109758
作者:
Zhu, Xian-Jin
;
Yu, Gui-Rui
;
Chen, Zhi
;
Zhang, Wei-Kang
;
Han, Lang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/12/04
Carbon cycles
Eddy covariance
Terrestrial ecosystems
Machine learning
Ecosystem responses
Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 14
作者:
Liu, Jiayuan
;
Zhang, Xianglei
;
Chen, Guofeng
;
Shao, Qiang
;
Zou, Yi
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/01/16
Phosphodiesterase-4 (PDE4)
PDE5
Inhibitor
Drug repurposing
Crystal structure
Structure -guided optimization
Improving the tribological behavior of CrN film by PVD/HVOF design
期刊论文
OAI收割
Surface and Coatings Technology, 2023, 期号: 0, 页码: 130171
作者:
Li Liu
;
Lei Shao
;
Wensheng Li
;
Lunlin Shang
;
Chunzhi Zhang
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/01/04
Disclosing the most intense magmatic flare-up in southern Tibet: Insights from study of the Pangduo volcanic-plutonic complex
期刊论文
OAI收割
LITHOS, 2023, 卷号: 454, 页码: 15
作者:
Chen, Hou-Bin
;
Ji, Wei-Qiang
;
Zhang, Shao-Hua
;
Jiang, Hehe
;
Xu, Qiang
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2023/12/29
Gangdese arc
Southern Tibet
Pangduo volcanic -plutonic complex
Magmatic process
Flare-up
Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers
期刊论文
OAI收割
CELL RESEARCH, 2023, 页码: 13
作者:
Wang, Xinwei
;
Wang, Mu
;
Xu, Tuo
;
Feng, Ye
;
Shao, Qiang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches
期刊论文
OAI收割
CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 18, 页码: 4681-4696
作者:
Shao, Qiang
;
Xiong, Muya
;
Li, Jiameng
;
Hu, Hangchen
;
Su, Haixia
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
Mapping Chinese annual gross primary productivity with eddy covariance measurements and machine learning
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 857, 页码: 18
作者:
Zhu, Xian-Jin
;
Yu, Gui-Rui
;
Chen, Zhi
;
Zhang, Wei-Kang
;
Han, Lang
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/12/09
Carbon cycle
Climate change
Eddy covariance
Terrestrial ecosystem
Machine learning
Scale extension