中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
广州生物医药与健康研... [8]
生态环境研究中心 [3]
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OAI收割 [34]
内容类型
期刊论文 [34]
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2025 [1]
2024 [4]
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2022 [3]
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2019 [3]
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Pharmacolo... [8]
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Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Tumor-specific delivery of clickable inhibitor for PD-L1 degradation and mitigating resistance of radioimmunotherapy
期刊论文
OAI收割
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 46, 页码: 17
作者:
Hou, Bo
;
Ye, Jiayi
;
Huang, Lujia
;
Cheng, Wenhao
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/12/16
Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14
作者:
Yang, Qi
;
Xue, Bao
;
Liu, Fengjiang
;
Lu, Yongzhi
;
Tang, Jielin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/07/12
Quantitative Characterization of the Volatility Distribution of Organic Aerosols in a Polluted Urban Area: Intercomparison Between Thermodenuder and Molecular Measurements
期刊论文
OAI收割
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2024, 卷号: 129, 期号: 4, 页码: 25
作者:
Chen, Wei
;
Hu, Weiwei
;
Tao, Zi
;
Cai, Yiyu
;
Cai, Mingfu
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/09/12
volatility
organic aerosols
particle-phase organic nitrate
thermodenuder
SIMPOL
gas/particle partitioning
formula/element-based method
Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:
Chang, Qi
;
Li, Jiayi
;
Deng, Yue
;
Zhou, Ruilin
;
Wang, Bingwei
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/03/25
Si-Based High-Entropy Anode for Lithium-Ion Batteries
期刊论文
OAI收割
SMALL METHODS, 2023, 页码: 10
作者:
Lei, Xincheng
;
Wang, Yingying
;
Wang, Jiayi
;
Su, Yi
;
Ji, Pengxiang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/01/08
high entropy effect
Li ion batteries
mechanical properties
Si anodes
structural integrity
Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20
作者:
Chen, Yuting
;
Shi, Qiongyu
;
Yang, Hong
;
Li, Jiayi
;
Zhou, Kaixin
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/04/10
Epigenetic
PRMT5 inhibitor
Nucleoside derivatives
Structure-activity Relationship Prodrug
Redox Dyshomeostasis with Dual Stimuli-Activatable Dihydroartemisinin Nanoparticles to Potentiate Ferroptotic Therapy of Pancreatic Cancer
期刊论文
OAI收割
SMALL METHODS, 2022, 页码: 13
作者:
Wang, Yingjie
;
Chen, Fangmin
;
Zhou, Huiling
;
Huang, Lujia
;
Ye, Jiayi
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2023/04/10
combinatory therapy
dual stimuli-responsive
ferroptosis
immunotherapy
pancreatic cancer
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 124, 页码: 15
作者:
Liu, Ruiqi
;
Yang, Hong
;
Chen, Zonglong
;
Zhou, Kaixin
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/08/16
Epigenetics
p300
CBP
Bromodomain inhibitors
CCS1477
Structure-Aided Design, Synthesis, and Biological Evaluation of Potent and Selective Non-Nucleoside Inhibitors Targeting Protein Arginine Methyltransferase 5
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 11, 页码: 7854-7875
作者:
Rong, Deqin
;
Zhou, Kaixin
;
Fang, Wei
;
Yang, Hong
;
Zhang, Yi
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/08/16