机构

• 上海药物研究所 [53]
• 广州生物医药与健康研... [3]
• 大连化学物理研究所 [3]
• 上海应用物理研究所 [1]
• 中国科学院大学 [1]
• 上海生物化学与细胞生... [1]
• 更多

采集方式

• OAI收割 [61]
• iSwitch采集 [2]

内容类型

• 期刊论文 [62]
• 学位论文 [1]

发表日期

• 2024 [2]
• 2023 [4]
• 2022 [10]
• 2021 [5]
• 2020 [9]
• 2019 [7]
• 更多

学科主题

• Pharmacolo... [2]
• 化学工程 [1]

筛选

浏览/检索结果: 共63条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486 作者:  Chang, Qi;  Li, Jiayi;  Deng, Yue;  Zhou, Ruilin;  Wang, Bingwei   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14 作者:  Chen, Xuetao   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/02/27 BET  BD1  Bromodomain  Brain-permeable  Multiple sclerosis   Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18 作者:  Zhang, Jingyu;  Duan, Haiting;  Gui, Renzhao;  Wu, Mingfei;  Shen, Liteng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/19 Acute myeloid leukemia  Bromodomain-containing protein 9  Proteolysis-targeting chimera  Orally bioavailable  Docking   Discovery of 1H-Imidazo[4,5-b]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 13, 页码: 8725-8744 作者:  Chen, Xuetao;  Cao, Danyan;  Liu, Chihong;  Meng, Fanying;  Zhang, Zijian   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Discovery of new small molecule inhibitors of the BPTF bromodomain 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 134, 页码: 106453 作者:  Liang, Xiaochen;  Cao, Yu;  Duan, Zhe;  Wang, Mingchen;  Zhang, Naixia   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/03/27 BPTF bromodomain  BPTF inhibitors  HTRF  c-Myc   Cyclization strategy leads to highly potent Bromodomain and extra-terminal (BET) Bromodomain inhibitors for the treatment of acute liver injury 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 247, 页码: 13 作者:  Chen, Chao;  Lu, Tian;  Chen, Panyu;  Li, Zizhou;  Yang, Yaxi   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/04/10 BET Bromodomains  Acute liver injury  Anti-inflammatory activity  Inhibitors  Tetracyclic compounds   Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non-Small Cell Lung Cancer Cells 期刊论文  OAI收割 MOLECULAR CANCER RESEARCH, 2022, 卷号: 20, 期号: 12, 页码: 1785-1798 作者:  Sun, Lin;  Wu, Qian;  Huan, Xia-Juan;  Tian, Chang-Qing;  Wang, Ying-Qing   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 Proteomic characterization of post-translational modifications in drug discovery 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 18 作者:  Zhai, Lin-hui;  Chen, Kai-feng;  Hao, Bing-bing;  Tan, Min-jia   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/04/10 proteomics  protein post-translational modification  drug target  off-target  drug mechanism  precision medicine   Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13 作者:  Luo, Menglan;  Wu, Qian;  Yang, Yueyue;  Sun, Lin;  Huan, Xiajuan   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/08/30 BET inhibitor  BRD4  Bivalent inhibitor  Anticancer   BPTF inhibition antagonizes colorectal cancer progression by transcriptionally inactivating Cdc25A 期刊论文  OAI收割 REDOX BIOLOGY, 2022, 卷号: 55, 页码: 16 作者:  Guo, Ping;  Zu, Shijia;  Han, Shilong;  Yu, Wendan;  Xue, Guoqing   |  收藏  |  浏览/下载：33/0  |  提交时间：2022/12/13 Colorectal cancer  BPTF  Cdc25A  c-Myc  Cell cycle