机构

• 上海药物研究所 [18]
• 广州生物医药与健康研... [4]
• 武汉物理与数学研究所 [1]

采集方式

• OAI收割 [23]

内容类型

• 期刊论文 [23]

发表日期

• 2024 [3]
• 2023 [5]
• 2022 [6]
• 2021 [3]
• 2020 [1]
• 2016 [2]
• 更多

学科主题

• Cell Biolo... [2]
• Science & ... [2]

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of Novel Nonpeptidic and Noncovalent Small Molecule 3CLpro Inhibitors as anti-SARS-CoV-2 Drug Candidate 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12760-12783 作者:  Jiang, Zhidong;  Feng, Bo;  Chen, Lu;  Nie, Tianqing;  Chen, Shizhao   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/09/26 Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3286-3290 作者:  Zheng, Miao;  Feng, Bo;  Zhang, Yumin;  Liu, Xin;  Zhao, Na   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/08/22 Non-covalent PLpro inhibitors  Antiviral activity  Structural-based drug design  Imidazo[4,5-b]pyridine scaffold   Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14 作者:  Xie, Xiong;  Lan, Qiaoshuai;  Zhao, Jinyi;  Zhang, Sulin;  Liu, Lu   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/05/07 Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：35/0  |  提交时间：2024/03/25 Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18 作者:  Ren, Pengxuan;  Li, Hui;  Nie, Tianqing;  Jian, Xiaoqin;  Yu, Changyue   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/10/17 Discovery of novel non-peptidic and non-covalent small-molecule 3CL(pro) inhibitors as potential candidate for COVID-19 treatment 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 4 作者:  Jiang, Zhidong;  Feng, Bo;  Zhang, Yumin;  Nie, Tianqing;  Liu, Hong   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/10/17 Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2 期刊论文  OAI收割 European journal of medicinal chemistry, 2023, 卷号: 249, 页码: 115129 作者:  Ren, Pengxuan;  Yu, Changyue;  Zhang, Ruxue;  Nie, Tianqing;  Hu, Qiaoyu   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/03/26 High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors 期刊论文  OAI收割 PROTEIN & CELL, 2023, 卷号: 14, 期号: 1, 页码: 17-27 作者:  Zang, Yi;  Su, Mingbo;  Wang, Qingxing;  Cheng, Xi;  Zhang, Wenru   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/03/27 high-throughput screening  SARS  CoV-2  main  papain-like  proteases   Synthesis of maleimide-braced peptide macrocycles and their potential anti-SARS-CoV-2 mechanisms 期刊论文  OAI收割 CHEMICAL COMMUNICATIONS, 2022, 页码: 4 作者:  Li, Jian;  Sun, Jina;  Zhang, Xianglei;  Zhang, Ruxue;  Wang, Qian   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/04/10 In vitro and in vivo evaluation of the main protease inhibitor FB2001 against SARS-CoV-2 期刊论文  OAI收割 ANTIVIRAL RESEARCH, 2022, 卷号: 208, 页码: 10 作者:  Shang, Weijuan;  Dai, Wenhao;  Yao, Cheng;  Xu, Ling;  Tao, Xiangming   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/04/10 SARS-CoV-2  SARS-CoV-2 variants  FB2001  Main protease  PBPK  Anti-SARS-CoV-2 in vivo