中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
上海应用物理研究所 [2]
地球化学研究所 [1]
半导体研究所 [1]
广州能源研究所 [1]
采集方式
OAI收割 [18]
内容类型
期刊论文 [18]
发表日期
2022 [1]
2019 [1]
2018 [1]
2016 [1]
2015 [2]
2014 [2]
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学科主题
半导体材料 [1]
环境地球化学 [1]
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浏览/检索结果:
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Thermodynamic analyses of a novel ejector enhanced dual-temperature air source heat pump cycle with self-defrosting
期刊论文
OAI收割
APPLIED THERMAL ENGINEERING, 2022, 卷号: 215, 页码: 16
作者:
Li, Shengyu
;
Lu, Jun
;
Li, Wuyan
;
Zhang, Yunqian
;
Huang, Sheng
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/12/03
Ejector
Dual-temperature air-source heat pump
Different operating cases
Defrosting method
Efficiency improvement
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:
Zhang, Xianglei
;
Dong, Guangyu
;
Li, Heng
;
Chen, Wuyan
;
Li, Jian
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells
期刊论文
OAI收割
HAEMATOLOGICA, 2018, 卷号: 103, 期号: 9, 页码: 1472-1483
作者:
Wu, Dang
;
Wang, Wanyan
;
Chen, Wuyan
;
Lian, Fulin
;
Lang, Li
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
Structure-Based Discovery of PDEs Inhibitors
期刊论文
OAI收割
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2016, 卷号: 16, 期号: 9, 页码: 917-933
作者:
Li, Li
;
Chen, Wuyan
;
Chen, Tiantian
;
Ren, Jing
;
Xu, Yechun
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Crystal structure
Cyclic nucleotide signalling pathway
Family-selective inhibitor
Medicinal chemistry
Phosphodiesterases
Structure-based drug design
Design, synthesis and biological evaluation of tasiamide B derivatives as BACE1 inhibitors
期刊论文
OAI收割
Bioorganic & medicinal chemistry, 2015, 卷号: 23, 期号: 9, 页码: 1963-74
作者:
Liu, Jian
;
Chen, Wuyan
;
Xu, Yechun
;
Ren, Sumei
;
Zhang, Wei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Impacts of Mercury Pollution Controls on Atmospheric Mercury Concentration and Occupational Mercury Exposure in a Hospital
期刊论文
OAI收割
Biological Trace Element Research, 2015, 卷号: 168, 期号: 2, 页码: 330-334
Ping Li
;
Yan Yang
;
Wuyan Xiong
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2016/09/02
Pediatric ward
Atmospheric mercury
Urine mercury
Mercury pollution control
Impact
Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 87, 页码: 765-781
作者:
Chen, Danqi
;
Shen, Aijun
;
Li, Jian
;
Shi, Feng
;
Chen, Wuyan
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
HSP90
Fragment-based drug discovery
Crystallography
Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 11, 页码: 2525-2529
作者:
Ren, Jing
;
Li, Jian
;
Wang, Yueqin
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Heat shock protein
HSP90
Fragment-based drug discovery
Anticancer
Discovery of pyrazole as C-terminus of selective BACE1 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 68, 页码: 270-283
作者:
Zou, Yiquan
;
Xu, Lei
;
Chen, Wuyan
;
Zhu, Yiping
;
Chen, Tiantian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Alzheimer's disease
BACE1
C-terminus
Click chemistry
In situ screening assay
Pyrazole
Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 10, 页码: 3833-3851
作者:
Zhao, Lele
;
Cao, Danyan
;
Chen, Tiantian
;
Wang, Yingqing
;
Miao, Zehong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08