中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
半导体研究所 [2]
水生生物研究所 [1]
动物研究所 [1]
采集方式
OAI收割 [15]
内容类型
期刊论文 [15]
发表日期
2025 [2]
2024 [1]
2023 [2]
2022 [5]
2021 [2]
2020 [2]
更多
学科主题
半导体物理 [1]
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浏览/检索结果:
共15条,第1-10条
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Ligand-binding assays validated for quantitative bioanalysis of a novel antibody-drug conjugate in monkey serum and related application in a nonclinical study
期刊论文
OAI收割
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2025, 卷号: 131, 页码: 11
作者:
Hou, Yingying
;
Miao, Jie
;
Sun, Yajun
;
Shi, Lili
;
Lu, Ouyang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
ADC
LBA
Validation
GLP
PK
Zexie-Baizhu Decoction ameliorates non-alcoholic fatty liver disease through gut-adipose tissue crosstalk
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 337, 页码: 14
作者:
Shi, Jingying
;
Liu, Yawen
;
Zhang, Zijia
;
Zhong, Xianchun
;
Cao, Yuhan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/10/21
Zexie-Baizhu Decoction
Traditional Chinese medicine
Akkermansia muciniphila
Bile acids
Short chain fatty acid
Lipidomics
Next-generation anti-PD-L1/IL-15 immunocytokine elicits superior antitumor immunity in cold tumors with minimal toxicity
期刊论文
OAI收割
CELL REPORTS MEDICINE, 2024, 卷号: 5, 期号: 5, 页码: 20
作者:
Shi, Wenqiang
;
Liu, Nan
;
Liu, Zexin
;
Yang, Yuqi
;
Zeng, Qiongya
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/09/26
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 5, 页码: 2384-2391
作者:
Xu, Zhijian
;
Shi, Danrong
;
Han, Jianbao
;
Ling, Yun
;
Jiang, Xiangrui
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/03/27
Development, Validation and Application of a Bridging ELISA for Detection of Antibodies against GQ1001 in Cynomolgus Monkey Serum
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 4, 页码: 1684
作者:
Liu, Tingting
;
Sun, Yajun
;
Deng, Xiaojie
;
Shi, Lili
;
Chen, Wenyi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/27
antibody-drug conjugate
immunogenicity
anti-drug antibody
bridging ELISA
D3AI-Spike: A deep learning platform for predicting binding affinity between SARS-CoV-2 spike receptor binding domain with multiple amino acid mutations and human angiotensin-converting enzyme 2
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2022, 卷号: 151, 页码: 8
作者:
Han, Jiaxin
;
Liu, Tingting
;
Zhang, Xinben
;
Yang, Yanqing
;
Shi, Yulong
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
D3AI-Spike
ELISA
Protein -protein interaction
COVID-19
Deep learning
Exploring the Binding Affinity and Mechanism between ACE2 and the Trimers of Delta and Omicron Spike Proteins by Molecular Dynamics Simulation and Bioassay
期刊论文
OAI收割
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2022, 页码: 11
作者:
Zhou, Liping
;
Liu, Tingting
;
Mo, Mengxia
;
Shi, Yulong
;
Wu, Leyun
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/11/11
Multi-Omics Integration Analysis Identifies Lipid Disorder of a Non-Alcoholic Fatty Liver Disease (NAFLD) Mouse Model Improved by Zexie-Baizhu Decoction
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 15
作者:
Cao, Yuhan
;
Shi, Jingying
;
Song, Luyao
;
Xu, Junjiu
;
Lu, Henglei
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/08/16
NAFLD
metabolomics
transcriptomics
lipid metabolism
traditional Chinese medicine
One-step synthesis of site-specific antibody-drug conjugates by reprograming IgG glycoengineering with LacNAc-based substrates
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2417-2428
作者:
Shi, Wei
;
Li, Wanzhen
;
Zhang, Jianxin
;
Li, Tiehai
;
Song, Yakai
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/08/16
Site-specific ADCs
ENGase
LacNAc
One-step assembly
Potent in vivo efficacy
Predicting spike protein NTD mutations of SARS-CoV-2 causing immune evasion by molecular dynamics simulations
期刊论文
OAI收割
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2022, 卷号: 24, 期号: 5, 页码: 3410-3419
作者:
Zhou, Liping
;
Wu, Leyun
;
Peng, Cheng
;
Yang, Yanqing
;
Shi, Yulong
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/06/15