中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
西北高原生物研究所 [9]
上海光学精密机械研究... [4]
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期刊论文 [52]
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2023 [2]
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Marine & F... [1]
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Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:
Zhu, Yueyue
;
Liu, Bo
;
Chen, Zonglong
;
Wang, Xianyang
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/12/08
Toll -like receptor 2/6 agonists
PamCS
Structure-activity relationship
Lipopeptide
Immunostimulants
Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 5
作者:
Wang, Yujie
;
Xu, Keshi
;
Liu, Hongchun
;
Zhang, Wei
;
Hu, Chun
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/12/19
Auristatin E
beta-Glucuronidase
Antiproliferation
Tumor microenvironment
Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 16
作者:
Chen, Zonglong
;
Li, Jiayi
;
Yang, Hong
;
He, Yulong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/08/16
P300
Bromodomain inhibitors
CBP30
SBDD
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 124, 页码: 15
作者:
Liu, Ruiqi
;
Yang, Hong
;
Chen, Zonglong
;
Zhou, Kaixin
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/08/16
Epigenetics
p300
CBP
Bromodomain inhibitors
CCS1477
Sulphate Corrosion Mechanism of Ultra-High-Performance Concrete (UHPC) Prepared with Seawater and Sea Sand
期刊论文
OAI收割
POLYMERS, 2022, 卷号: 14, 期号: 5, 页码: 21
作者:
Sun, Xin
;
Li, Tianyu
;
Shi, Fangying
;
Liu, Xiaoyan
;
Zong, Yingxia
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/04/12
sea sand
polymer cement mortar
UHPC
sulphate corrosion
material characterization
X-CT
Synthesis of the analogs of plocabulin and their preliminary structure-activity relationship study
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 51, 页码: 5
作者:
Wang, Leiming
;
Li, Xin
;
Cui, Hong
;
Lei, Xinsheng
;
Liu, Hongchun
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/12/01
Marine nature products
Plocabulin
PM060184
Synthesis
Antiproliferation
A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro
期刊论文
OAI收割
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 12, 页码: 20
作者:
Zhang, Haiping
;
Yang, Yang
;
Li, Junxin
;
Wang, Min
;
Saravanan, Konda Mani
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/12/01
Investigation of the remote acyl group participation in glycosylation from conformational perspectives by using trichloroacetimidate as the acetyl surrogate
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 13, 页码: 1606-1615
作者:
Xu, Ke
;
Man, Qingmin
;
Zhang, Yang
;
Guo, Jia
;
Liu, Yichu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
Palladium-Catalysed C(sp(3))-H Glycosylation for the Synthesis of C-Alkyl Glycoamino Acids
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 5
作者:
Liu, Yichu
;
Wang, Yibing
;
Dai, Wenhao
;
Huang, Wei
;
Li, Yingxia
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
alpha-amino acids
C(sp(3))-H activation
C-alkyl glycosides
diastereoselectivity
palladium
Design, synthesis, and biological evaluation of a new class of histone acetyltransferase p300 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 171-190
作者:
Liu, Ruiqi
;
Zhang, Zhuqing
;
Yang, Hong
;
Zhou, Kaixin
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2020/07/01
p300 inhibitors
Epigenetics
Structure-activity relationship
Sensitive tumor cell proliferation
C646