中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
水生生物研究所 [6]
力学研究所 [1]
苏州纳米技术与纳米仿... [1]
青岛生物能源与过程研... [1]
上海营养与健康研究所 [1]
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OAI收割 [18]
内容类型
期刊论文 [18]
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2024 [2]
2023 [1]
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2020 [1]
2019 [2]
2018 [1]
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Environmen... [2]
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A thermodynamically-consistent non-isothermal phase-field model for probing evolution of crack propagation and phase transformation
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES, 2024, 卷号: 270, 页码: 17
作者:
Zhen, Yu
;
Wu, Kaijin
;
Lu, Yuyang
;
Liu, Mengqi
;
He, Linghui
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/05/14
Phase -field
Multiphysics field
Crack propagation
Phase transformation
Thermal -mechanical coupling
Discovery of an Ortho-Substituted
N
-Cyclopropylmethyl-7α-phenyl-6,14-
endo
ethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 9, 页码: 7112-7129
作者:
Li, Zixiang
;
Ye, Rufeng
;
He, Qian
;
Lu, Jiashuo
;
Sun, Yanting
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/06/27
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Temperature-Controlled Divergent Synthesis of Tetrasubstituted Alkenes and Pyrrolo[1,2-a]indole Derivatives via Iridium Catalysis
期刊论文
OAI收割
ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 页码: 14
作者:
Liu, Siyu
;
Mao, Hui
;
Qiao, Jin
;
Zhang, Xiaoning
;
Lu, Yangbin
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/11/04
Iridium
C-H activation
[3+2] annulation
Tetrasubstituted alkene
pyrrolo[1,2-a]indole
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:
Liu, Xiao
;
Jiang, Shuang
;
Kong, Linghui
;
Ye, Rongrong
;
Xiao, Li
  |  
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2021/05/24
Morphinans
arylacetamidyl substituent
kappa opioid receptor modulators
structure-activity relationships
TREK Channel Family Activator with a Well-Defined Structure-Activation Relationship for Pain and Neurogenic Inflammation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 7, 页码: 3665-3677
作者:
Qiu, Yunguang
;
Huang, Lu
;
Fu, Jie
;
Han, Chenxia
;
Fang, Jing
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12
作者:
Liao, Ping
;
Qiu, Yunguang
;
Mo, Yiqing
;
Fu, Jie
;
Song, Zhenpeng
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
Rosanortriterpene C, a 3,24-Dinor-2,4-seco-ursane Triterpene from the Fruits of Rosa laevigata var. leiocapus
期刊论文
OAI收割
CHEMICAL & PHARMACEUTICAL BULLETIN, 2019, 卷号: 67, 期号: 11, 页码: 1255-1258
作者:
Tian, Yunong
;
Feng, Lu
;
Li, Bailin
;
Hu, Juanjuan
;
Xie, Jindan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
ursane-type nortriterpene
oleanane-type nortriterpene
Rosa laevigata var. leiocapus
anti-inflammatory
Enhanced Single-Step Bioproduction of the Simvastatin Precursor Monacolin J in an Industrial Strain of Aspergillus terreus by Employing the Evolved Lovastatin Hydrolase
期刊论文
OAI收割
BIOTECHNOLOGY JOURNAL, 2018, 卷号: 13, 期号: 6
作者:
Liang, Bo
;
Huang, Xuenian
;
Teng, Yun
;
Liang, Yajing
;
Yang, Yong
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2018/12/21
Aspergillus Terreus
Directed Evolution
Lovastatin Hydrolase
Monacolin j
Simvastatin
Multipronged Therapeutic Effects of Chinese Herbal Medicine Qishenyiqi in the Treatment of Acute Myocardial Infarction
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8, 期号: -, 页码: 98
作者:
Wang, Yong
;
Lu, Linghui
;
Wang, Wei
;
Lin, Weili
;
Li, Chun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/12/09
Acute myocardial infarction
Qishenyiqi
anti-inflammation
dyslipidaemia
group significance analysis