机构

• 上海药物研究所 [5]
• 水生生物研究所 [5]
• 广州生物医药与健康研... [2]

采集方式

• OAI收割 [12]

内容类型

• 期刊论文 [12]

发表日期

• 2020 [2]
• 2019 [2]
• 2018 [5]
• 2017 [1]
• 2014 [2]

学科主题

• Pharmacolo... [2]

筛选

浏览/检索结果: 共12条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Telophase of the first cleavage is the key stage for optimally inducing mitotic gynogenesis in rice field eel (Monopterus albus) 期刊论文  OAI收割 AQUACULTURE, 2020, 卷号: 523, 期号: 1, 页码: 7 作者:  Luo, Hongrui;  Feng, Ke;  Chen, Ji;  Song, Yanlong;  Hou, Mingxi   |  收藏  |  浏览/下载：51/0  |  提交时间：2020/05/28 Monopterus albus  Mitotic gynogenesis  Heat shock  Common carp  Cleavage   Timing of gonadal development and dimorphic expression of sex-related genes in gonads during early sex differentiation in the Yellow River carp 期刊论文  OAI收割 AQUACULTURE, 2020, 卷号: 518, 期号: 1, 页码: 11 作者:  Jiang, Mouyan;  Jia, Shaoting;  Chen, Ji;  Chen, Kuangxin;  Ma, Wenge   |  收藏  |  浏览/下载：25/0  |  提交时间：2020/04/28 Yellow River carp  All-males  All-females  Window of sex determination  Gonadal sex differentiation   Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity 期刊论文  OAI收割 JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785 作者:  Zhu, Kongkai;  Shao, Jingwei;  Tao, Hongrui;  Yan, Xue;  Luo, Cheng   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 PRMT5 inhibitor  Anti-proliferative  Cellular target validation  Design and synthesis   Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 317-333 作者:  Shao, Jingwei;  Zhu, Kongkai;  Du, Daohai;  Zhang, Yuanyuan;  Tao, Hongrui   |  收藏  |  浏览/下载：25/0  |  提交时间：2020/07/01 PRMT5 inhibitors  N-Substituted 1,2,3,4-tetrahydroisoquinoline derivatives  Anti-tumor   Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2018, 卷号: 81, 页码: 289-298 作者:  Zhu, Kongkai;  Tao, Hongrui;  Song, Jia-Li;  Jin, Lu;  Zhang, Yuanyuan   |  收藏  |  浏览/下载：129/0  |  提交时间：2019/01/08 PRMT5 inhibitor  Arginine methylation  Virtual screening  Molecular docking  Molecular dynamics simulation   Alternative splicing of GnRH2 and GnRH2-associated peptide plays roles in gonadal differentiation of the rice field eel, Monopterus albus 期刊论文  OAI收割 GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2018, 卷号: 267, 页码: 9-17 作者:  Feng, Ke;  Luo, Hongrui;  Hou, Mingxi;  Li, Yongming;  Chen, Ji   |  收藏  |  浏览/下载：52/0  |  提交时间：2019/07/02 GnRH2  GnRH2-associated peptide  Alternative splicing  Gonadal differentiation  Rice field eel   Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 9, 页码: 1476-1483 作者:  Zhu, Kongkai;  Jiang, Chengshi;  Tao, Hongrui;  Liu, Jingqiu;  Zhang, Hua   |  收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08 PRMT5 inhibitor  Resynthesis  Virtual screening  Molecular docking  Molecular dynamics simulation   Production of YY Supermale and XY Physiological Female Common Carp for Potential Eradication of this Invasive Species 期刊论文  OAI收割 JOURNAL OF THE WORLD AQUACULTURE SOCIETY, 2018, 卷号: 49, 期号: 2, 页码: 315-327 作者:  Jiang, Mouyan;  Wu, Xingxing;  Chen, Kuangxin;  Luo, Hongrui;  Yu, Wei   |  收藏  |  浏览/下载：34/0  |  提交时间：2019/07/03 androgenesis  common carp  XY physiological female common carp  YY supermale common carp   Interaction assessments of the first S-adenosylmethionine competitive inhibitor and the essential interacting partner methylosome protein 50 with protein arginine methyltransferase 5 by combined computational methods 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 495, 期号: 1, 页码: 721-727 作者:  Zhu, Kongkai;  Jiang, Cheng-Shi;  Hu, Junchi;  Liu, Xigong;  Yan, Xue   |  收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 PRMT5 SAM competitive inhibitor  Molecular docking  Molecular dynamics simulation  Molecular mechanics/Poisson-Boltzmann surface area  PRMT5:MEP50 interaction   High efficient gene targeting in rice field eel Monopterus albus by transcription activator-like effector nucleases 期刊论文  OAI收割 SCIENCE BULLETIN, 2017, 卷号: 62, 期号: 3, 页码: 162-164 作者:  Feng, Ke;  Luo, Hongrui;  Li, Yongming;  Chen, Ji;  Wang, Yaping   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/09/29