机构

• 上海药物研究所 [6]

采集方式

• OAI收割 [6]

内容类型

• 期刊论文 [6]

发表日期

• 2024 [1]
• 2018 [1]
• 2013 [3]
• 2008 [1]

学科主题

筛选

浏览/检索结果: 共6条，第1-6条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Single Amine or Guanidine Modification on Norvancomycin and Vancomycin to Overcome Multidrug-Resistance through Augmented Lipid II Binding and Increased Membrane Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 22, 页码: 20639-20663 作者:  Bian, Xiaolei;  Chen, Zhifu;  Li, Fang;  Xie, Yuanyuan;  Li, Yi   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/12/11 Targeting Gpr52 lowers mutant HTT levels and rescues Huntington's disease-associated phenotypes 期刊论文  OAI收割 BRAIN, 2018, 卷号: 141, 页码: 1782-1798 作者:  Song, Haikun;  Li, Hexuan;  Guo, Shimeng;  Pan, Yuyin;  Fu, Yuhua   |  收藏  |  浏览/下载：61/0  |  提交时间：2019/01/08 GPCR  target validation  polyQ  neurodegeneration  antagonists   Synthesis and in vitro cytotoxic evaluation of novel -(3,4,5-trimethoxyphenyl)pyridin-2()-one derivatives 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2013, 卷号: 17, 期号: 3, 页码: 435-444 作者:  Chen, Taijie;  Luo, Yu;  Sheng, Li;  Li, Jia;  Hu, Youhong   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Pyridin-2(1H)-one  Combretastatin A-4  Chan-Lam coupling reaction  Buchwald-Hartwig coupling reaction  HCT-116  Cytotoxicity  Cell cycle   Synthesis and biological evaluation of novel 1,6-diaryl pyridin-2(1H)-one analogs 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 64, 页码: 613-620 作者:  Chen, Taijie;  Luo, Yu;  Hu, Youhong;  Yang, Bo;  Lu, Wei   |  收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 Pyridin-2(1H)-one  Chan-Lam coupling reaction  Cytotoxicity  Antitumor activity  Cell cycle   Cu-mediated selective O-arylation on C-6 substituted pyridin-2-ones 期刊论文  OAI收割 TETRAHEDRON LETTERS, 2013, 卷号: 54, 期号: 11, 页码: 1401-1404 作者:  Chen, Taijie;  Huang, Qingqing;  Luo, Yu;  Hu, Youhong;  Lu, Wei   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Chan Evans Lam cross-coupling  Arylboronic acids  Selectivity  O-arylation  Pyridin-2-ones   Synthesis and biological evaluation of novel isopropanolamine derivatives as non-peptide human immunodeficiency virus protease inhibitors 期刊论文  OAI收割 CHEMICAL & PHARMACEUTICAL BULLETIN, 2008, 卷号: 56, 期号: 8, 页码: 1147-1152 作者:  Zhou, Lijun;  Yang, Qingang;  Wang, Yong;  Hu, Youhong;  Luo, Xiaomin   |  收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 isopropanolamine derivative  protease inhibitors  biological evaluation  docking study  predictive model