中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
深圳先进技术研究院 [2]
广州生物医药与健康研... [2]
成都山地灾害与环境研... [1]
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OAI收割 [19]
内容类型
期刊论文 [17]
会议论文 [2]
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2024 [5]
2023 [1]
2022 [1]
2021 [2]
2020 [2]
2019 [1]
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Biotechnol... [2]
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Sodium oligomannate disrupts the adherence of Rib
high
bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 19
作者:
Wang, Xinyi
;
Xie, Zuoquan
;
Yuan, Jie
;
Jin, Enjing
;
Lian, Wen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/16
Integrated omics profiling reveals systemic dysregulation and potential biomarkers in the blood of patients with neuromyelitis optica spectrum disorders
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 18
作者:
Xie, Zuoquan
;
Zhou, Qinming
;
Hu, Jin
;
He, Lu
;
Meng, Huangyu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/12/11
Neuromyelitis optica spectrum disorders
Blood immune cells phenotyping
Plasma cytokine array
Plasma metabolomics
Biomarker
Multi-omics profiling reveals peripheral blood biomarkers of multiple sclerosis: implications for diagnosis and stratification
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 12
作者:
Zhou, Qinming
;
Xie, Zuoquan
;
He, Lu
;
Sun, Guangqiang
;
Meng, Huanyu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/10/21
multiple sclerosis
multi-omics
blood immune phenotyping
proteomic
metabolomic
clinically isolated syndrome
secondary progressive MS
GV-971 attenuates the progression of neuromyelitis optica in murine models and reverses alterations in gut microbiota and associated peripheral abnormalities
期刊论文
OAI收割
CNS NEUROSCIENCE & THERAPEUTICS, 2024, 卷号: 30, 期号: 7, 页码: 15
作者:
Yang, Xinying
;
Zhangyi, Zhongheng
;
Yu, Aisong
;
Zhou, Qinming
;
Xia, Aihua
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/22
gut microbiota
GV-971
neuroinflammation
Neuromyelitis optica spectrum disorders
NMO-IgG
Integrated multi-omics analysis reveals gut microbiota dysbiosis and systemic disturbance in major depressive disorder
期刊论文
OAI收割
PSYCHIATRY RESEARCH, 2024, 卷号: 334, 页码: 12
作者:
Xie, Zuoquan
;
Huang, Jingjing
;
Sun, Guangqiang
;
He, Shen
;
Luo, Zhiyu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/05/22
Major depressive disorder
Peripheral changes
Gut microbiota
Immune phenotyping
Multiomics
Biomarkers
Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 10
作者:
Li, Peizhuo
;
Tian, Yucheng
;
Shang, Qinghong
;
Tang, Cailing
;
Hou, Zeng
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/10/17
NPAS3
Covalent inhibitor
Protein -protein interaction
5-nitrothiazole warhead
The p300 Inhibitor A-485 Exerts Antitumor Activity in Growth Hormone Pituitary Adenoma
期刊论文
OAI收割
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2022, 页码: 10
作者:
Ji, Chenxing
;
Xu, Wen
;
Ding, Hong
;
Chen, Zhengyuan
;
Shi, Chengzhang
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/06/15
p300
A-485
growth hormone pituitary adenoma
Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52, 页码: 12
作者:
Ding, Hong
;
Pei, Yuan
;
Li, Yuanqing
;
Xu, Wen
;
Mei, Lianghe
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/06/15
Epigenetics
Histone acetyltransferase
P300/CBP
Ovarian cancer
Observations of Forbush Decreases of Cosmic-Ray Electrons and Positrons with the Dark Matter Particle Explorer
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2021, 卷号: 920, 期号: 2, 页码: 10
作者:
Alemanno, Francesca
;
An, Qi
;
Azzarello, Philipp
;
Barbato, Felicia Carla Tiziana
;
Bernardini, Paolo
  |  
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2021/12/08
Solar coronal mass ejections
Forbush effect
Cosmic rays
Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9
作者:
Han, Jie
;
Tian, Yucheng
;
Yu, Liang
;
Zhang, Qilin
;
Xu, Xi
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/12/24
Ubiquitination
High throughput screening
Drug discovery
USP8