中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共102条,第1-10条 帮助

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Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel HsClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:  
Sun, Mingyang;  Chen, Beijing;  Teng, Dan;  Zhao, Hongshen;  Liao, Yilie
  |  收藏  |  浏览/下载:11/0  |  提交时间:2025/04/01
π-HuB: the proteomic navigator of the human body 期刊论文  OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:  
He, Fuchu;  Aebersold, Ruedi;  Baker, Mark S.;  Bian, Xiuwu;  Bo, Xiaochen
  |  收藏  |  浏览/下载:10/0  |  提交时间:2025/04/01
A peptide-centric local stability assay enables proteome-scale identification of the protein targets and binding regions of diverse ligands 期刊论文  OAI收割
NATURE METHODS, 2024, 页码: 17
作者:  
Li, Kejia;  Chen, Shijie;  Wang, Keyun;  Wang, Yan;  Xue, Lianji
  |  收藏  |  浏览/下载:12/0  |  提交时间:2025/01/14
Emerging Pollutants 期刊论文  OAI收割
PROGRESS IN CHEMISTRY, 2024, 卷号: 36, 期号: 11, 页码: 1607-1784
作者:  
Wang, Yawei;  Zhang, Qiurui;  Yu, Nanyang;  Wang, Yuan;  Wei, Si
  |  收藏  |  浏览/下载:12/0  |  提交时间:2025/04/03
Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:  
Chen, Beijing;  Sun, Mingyang;  Zhang, Chun;  Huang, Qi;  Teng, Dan
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/12/25
Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12735-12759
作者:  
Liu, Zhi;  Jiang, Kailong;  Liu, Yan;  Li, Junfei;  Huang, Siqi
  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/09/26
Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase 期刊论文  OAI收割
ACS CHEMICAL BIOLOGY, 2024, 页码: 12
作者:  
Zhang, Huimin;  Xu, Dounan;  Huang, Hongchan;  Jiang, Hao;  Hu, Linghao
  |  收藏  |  浏览/下载:19/0  |  提交时间:2024/05/07
Accelerated Primal-Dual Projection Neurodynamic Approach with time Scaling for Linear and set Constrained Convex Optimization Problems 期刊论文  OAI收割
IEEE/CAA Journal of Automatica Sinica, 2024, 卷号: 11, 期号: 6, 页码: 1485-1498
作者:  
You Zhao;  Xing He;  Mingliang Zhou;  Tingwen Huang
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/05/22
Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 22, 页码: 15269-15287
作者:  
Hu, Linghao;  Li, Huiyun;  Qin, Junlin;  Yang, Dan;  Liu, Jieming
  |  收藏  |  浏览/下载:44/0  |  提交时间:2024/02/27
Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis 期刊论文  OAI收割
CELL METABOLISM, 2023, 卷号: 35, 期号: 10, 页码: 1752-+
作者:  
Kuang, Junliang;  Wang, Jieyi;  Li, Yitao
  |  收藏  |  浏览/下载:23/0  |  提交时间:2023/12/08