机构

• 上海药物研究所 [74]
• 生物物理研究所 [2]
• 大连化学物理研究所 [2]
• 上海营养与健康研究所 [2]

采集方式

• OAI收割 [80]

内容类型

• 期刊论文 [79]
• 会议论文 [1]

发表日期

• 2025 [2]
• 2024 [8]
• 2023 [3]
• 2022 [6]
• 2021 [4]
• 2020 [1]
• 更多

学科主题

• Immunology [2]
• Cell Biolo... [1]
• Chemistry,... [1]

筛选

浏览/检索结果: 共80条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Phosphatidylinositol 4,5-bisphosphate activation mechanism of human KCNQ5 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2025, 卷号: 122, 期号: 14, 页码: 11 作者:  Yang, Zhenni;  Zheng, Yueming;  Ma, Demin;  Wang, Long;  Zhang, Jiatong   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/06/23 KCNQ  PIP2  ligand activation  structure  mechanism   A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics of BGT-002, a Novel ATP-Citrate Lyase Inhibitor, in Healthy Chinese Subjects 期刊论文  OAI收割 DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 卷号: 19, 页码: 1783-1794 作者:  Liu, Yun;  Yu, Chengyin;  Zhang, Yifan;  Xie, Zhifu;  Wang, Yating   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/04/24 safety  tolerability  pharmacokinetics  pharmacodynamics  BGT-002  novel ACLY inhibitor   Synthesis and Biological Activity of Tetracyclic Dispiro Core Derivatives of Natural Products Dispirocochlearoids A-C 期刊论文  OAI收割 ORGANIC LETTERS, 2024, 卷号: 26, 期号: 45, 页码: 9654-9658 作者:  Pei, Junping;  Wang, Ying;  Shi, Shengjie;  Chen, Linhai;  Yin, Jianpeng   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/12/11 Discovery of Alkyl Conjugated Diene Diacids as Novel ACLY Inhibitors 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 11, 页码: 3476-3489 作者:  Cheng, Tingting;  Song, Gaolei;  Cheng, Long;  Wang, Fan;  Sun, Xinyu   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/02/28 metabolic diseases  ATP-citrate lyase (ACLY)  lipogenesis  ACLY inhibitors  dienyldicarboxylic acid   A brain-to-gut signal controls intestinal fat absorption 期刊论文  OAI收割 NATURE, 2024, 页码: 27 作者:  Lyu, Qianqian;  Xue, Wenzhi;  Liu, Ruixin;  Ma, Qinyun;  Kasaragod, Vikram Babu   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/11/26 Discovery of GPR84 Fluorogenic Probes Based on a Novel Antagonist for GPR84 Bioimaging 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 16 作者:  Xiao, Yufeng;  Chen, Jing;  Li, Shaoxian;  Zhang, Qing;  Liu, Yin   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/08/22 Simultaneous determination of BGT-002 and its acyl glucuronide metabolite ZM326E-M2 in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 243, 页码: 8 作者:  Zhu, Xueran;  Cui, Shumin;  Liu, Xinjing;  Zhang, Mei;  Xie, Zhifu   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/05/31 ATP-Citrate Lyase  BGT-002  Acyl glucuronide metabolite  Pseudo-MRM  LC-MS/MS  Pharmacokinetics   Polyphenol Compound 18a Modulates UCP1-Dependent Thermogenesis to Counteract Obesity 期刊论文  OAI收割 BIOMOLECULES, 2024, 卷号: 14, 期号: 6, 页码: 21 作者:  Wen, Xueping;  Song, Yufei;  Zhang, Mei;  Kang, Yiping;  Chen, Dandan   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/08/22 18a  adipocytes  polyphenols  thermogenesis  UCP1   Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18 作者:  Zhuo, Ning;  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Yin, Jianpeng   |  收藏  |  浏览/下载：36/0  |  提交时间：2024/03/25 Type 2 Diabetes  TGR5 agonist  Betulinic acid  Gut-restricted  Gallbladder-filling effects  Kinetophores   Design, Synthesis, and Structure-Activity Relationship of Novel Potent and Highly Selective Cysteinyl Leukotriene Receptor 1 (CysLT1R) Antagonists 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 1, 页码: 259-276 作者:  Wang Jingyi;  Liu Jinyu;  Chen Dongsheng;  Chen Huayan;  Xie Xin   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/05/07 cysteinyl leukotriene  cysteinyl leukotriene receptor 1 (CysLT1R)  selective antagonists