机构

• 上海药物研究所 [6]
• 地理科学与资源研究所 [2]
• 大连化学物理研究所 [2]
• 上海光学精密机械研究... [1]

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [11]

发表日期

• 2024 [1]
• 2023 [2]
• 2022 [1]
• 2021 [3]
• 2016 [1]
• 2015 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18 作者:  Zhuo, Ning;  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Yin, Jianpeng   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/25 Type 2 Diabetes  TGR5 agonist  Betulinic acid  Gut-restricted  Gallbladder-filling effects  Kinetophores   Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 2, 页码: 739-753 作者:  Xie, Zhifu;  Zhang, Mei;  Song, Qian;  Cheng, Long;  Zhang, Xinwen   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/03/27 Hypercholesterolemia  Atherosclerosis  Liver  ATP-Citrate lyase (ACLY)  Lipogenesis  Cholesterol efflux  ACLY inhibitor   Temperature-related mortality in China from specific injury 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1 作者:  Hu, Jianxiong;  He, Guanhao;  Meng, Ruilin;  Gong, Weiwei;  Ren, Zhoupeng   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/04 Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21 作者:  Zhang, Chenlu;  Liu, Yameng;  Wang, Ying;  Ge, Xie;  Jiao, Tingying   |  收藏  |  浏览/下载：34/0  |  提交时间：2022/11/11 Optimization and Development of a Scalable Palladium-Catalyzed C-H Activation Process for the Geometry-Selective Preparation of Kilograms of YLF466D, a Potent AMP-Activated Protein Kinase Activator 期刊论文  OAI收割 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 10, 页码: 2260-2269 作者:  Yin, Jianpeng;  Zhan, Desheng;  Ma, Hui;  Liu, Huanan;  Yu, Lifang   |  收藏  |  浏览/下载：21/0  |  提交时间：2021/12/16 YLF466D  AMPK activator  glucose metabolism  lipid metabolism  MIRI  domino reaction  C-H activation   Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199 作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan   |  收藏  |  浏览/下载：42/0  |  提交时间：2021/11/04 The assessment of current mortality burden and future mortality risk attributable to compound hot extremes in China 期刊论文  OAI收割 SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 777, 页码: 8 作者:  He, Guanhao;  Xu, Yanjun;  Hou, Zhulin;  Ren, Zhoupeng;  Zhou, Maigeng   |  收藏  |  浏览/下载：119/0  |  提交时间：2021/08/19 Compound hot extremes  Mortality risk  Global warming  China   Design and Synthesis of Diacylglycerol Acyltransferase 1 Inhibitors Based on Aphadilactone C 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2016, 卷号: 36, 期号: 6, 页码: 1359-1367 作者:  Li Dan;  Yin Jianpeng;  Li Jingya;  Nan Fajun   |  收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 aphadilactone C  DGAT1  selective inhibitor  PF-04620110  AZD-7687   ψ-Bufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling 期刊论文  OAI收割 Oncotarget, 2015, 卷号: 6, 期号: 13, 页码: 11627 作者:  Jin Ding;  Wen Wen;  Daimin Xiang;  Peipei Yin;  Liu YF(刘艳芳) 收藏  |  浏览/下载：15/0  |  提交时间：2016/11/24 psi-Bufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling 期刊论文  OAI收割 oncotarget, 2015, 卷号: 6, 期号: 13, 页码: 11627-11639 作者:  Ding, Jin;  Wen, Wen;  Xiang, Daimin;  Yin, Peipei;  Liu, Yanfang 收藏  |  浏览/下载：51/0  |  提交时间：2015/11/17 psi-Bufarenogin  hepatocellular carcinoma  epithelial growth factor receptor  hepatocyte growth factor receptor