中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
采集方式
OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2025 [1]
2024 [1]
2023 [2]
2022 [1]
学科主题
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Discovery of Novel RNA Demethylase FTO Inhibitors Featuring an Acylhydrazone Scaffold with Potent Antileukemia Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 22
作者:
Liang, Xuewu
;
Huang, Yue
;
Ren, Hairu
;
Liu, Qi
;
Chen, Liang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/04/01
Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/04/09
The new direction of drug development: Degradation of undruggable targets through targeting chimera technology
期刊论文
OAI收割
MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54
作者:
Liang, Xuewu
;
Ren, Hairu
;
Han, Fengyang
;
Liang, Renwen
;
Zhao, Jiayan
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/01/16
chimeric design
degradation System
PROTAC
targeted degradation technology
undruggable targets
Rh(III)-Catalyzed Synthesis of Substituted Isoindoles through a Direct C-H Activation/[4+1] Annulation and Acyl Migration Cascade of Oxadiazolones with Diazo Compounds
期刊论文
OAI收割
ORGANIC LETTERS, 2023, 页码: 5
作者:
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
Discovery of Novel Imidazo[4,5-c]quinoline Derivatives to Treat Inflammatory Bowel Disease (IBD) by Inhibiting Multiple Proinflammatory Signaling Pathways and Restoring Intestinal Homeostasis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21
作者:
Liang, Xuewu
;
Xie, Yongle
;
Liu, Xuyi
;
Xu, Hui
;
Ren, Hairu
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/11/11