中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
近代物理研究所 [3]
力学研究所 [2]
理论物理研究所 [2]
合肥物质科学研究院 [2]
新疆生态与地理研究所 [1]
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期刊论文 [34]
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2025 [1]
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2020 [3]
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浏览/检索结果:
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Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 19
作者:
Yin, Wen
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/01
AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
He, Xin-heng
;
Li, Jun-rui
;
Shen, Shi-yi
;
Xu, H. Eric
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/01/14
AlphaFold
structure-based drug design
artificial intelligence
GPCR
structural biology
AI-driven antibody design with generative diffusion models: current insights and future directions
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
He, Xin-heng
;
Li, Jun-rui
;
Xu, James
;
Shan, Hong
;
Shen, Shi-yi
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/11/05
antibodies
generative model
diffusion
de novo antibody design
CDR optimization
model evaluation
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Wen, Xin
;
Zhang, Minmin
;
Duan, Zhiqiang
;
Suo, Yanrui
;
Lu, Weiwei
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2023/10/17
Nucleic acid drug vectors for diagnosis and treatment of brain diseases
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 53
作者:
Lu, Zhi-Guo
;
Shen, Jie
;
Yang, Jun
;
Wang, Jing-Wen
;
Zhao, Rui-Chen
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2023/05/19
AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Pei, Jin-peng
;
Wang, Yue
;
Ma, Lan-ping
;
Wang, Xin
;
Liu, Liang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/04/10
AXL
NSCLC
TNBC
M2-macrophage
antibody-drug conjugate
Solar ring mission: Building a panorama of the Sun and inner-heliosphere
期刊论文
OAI收割
ADVANCES IN SPACE RESEARCH, 2023, 卷号: 71, 期号: 1, 页码: 1146-1164
作者:
Wang, Yuming
;
Bai, Xianyong
;
Chen, Changyong
;
Chen, Linjie
;
Cheng, Xin
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2023/02/06
Space mission design
Solar cycles
Solar eruptions
Space weather
An Implantable Magnetic Vascular Scaffold for Circulating Tumor Cell Removal In Vivo
期刊论文
OAI收割
ADVANCED MATERIALS, 2022
作者:
Yin, Zhiwei
;
Shi, Rui
;
Xia, Xin
;
Li, Ling
;
Yang, Yanxia
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2022/12/23
adhesion repertoires
bioinspired ultrastructure
circulating tumor cell removal
magnetothermal response
vascular-like integrated trapped devices
Observations of Forbush Decreases of Cosmic-Ray Electrons and Positrons with the Dark Matter Particle Explorer
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2021, 卷号: 920, 期号: 2, 页码: 10
作者:
Alemanno, Francesca
;
An, Qi
;
Azzarello, Philipp
;
Barbato, Felicia Carla Tiziana
;
Bernardini, Paolo
  |  
收藏
  |  
浏览/下载:106/0
  |  
提交时间:2021/12/08
Solar coronal mass ejections
Forbush effect
Cosmic rays