中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [30]
地理科学与资源研究所 [1]
采集方式
OAI收割 [31]
内容类型
期刊论文 [31]
发表日期
2024 [1]
2023 [1]
2022 [2]
2021 [4]
2020 [1]
2019 [2]
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De
novo
design of SARS-CoV-2 main protease inhibitors with characteristic binding modes
期刊论文
OAI收割
STRUCTURE, 2024, 卷号: 32, 期号: 9, 页码: 12
作者:
Zhu, Yan
;
Meng, Jiaolong
;
Feng, Bo
;
Zhao, Yao
;
Zang, Yi
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/10/21
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors
期刊论文
OAI收割
PROTEIN & CELL, 2023, 卷号: 14, 期号: 1, 页码: 17-27
作者:
Zang, Yi
;
Su, Mingbo
;
Wang, Qingxing
;
Cheng, Xi
;
Zhang, Wenru
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/27
high-throughput screening
SARS
CoV-2
main
papain-like
proteases
Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 8
作者:
Li, Linjie
;
Su, Mingbo
;
Lu, Weiwei
;
Song, Hongzhi
;
Liu, Jiaxiang
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/09/30
DNA encoded library
covalent library
library design
covalent inhibitors
Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 4335-4349
作者:
Li, Chunpu
;
Su, Mingbo
;
Zhu, Wei
;
Kan, Weijuan
;
Ge, Tianpeng
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/06/15
Design, Synthesis, and Biological Evaluation of HDAC Degraders with CRBN E3 Ligase Ligands
期刊论文
OAI收割
MOLECULES, 2021, 卷号: 26, 期号: 23, 页码: 19
作者:
Lu, Yingxin
;
Sun, Danwen
;
Xiao, Donghuai
;
Shao, Yingying
;
Su, Mingbo
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/06/15
HDAC degraders
CRBN ligands
proteins of interest
benzyl alcohol linkage
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
Design, Synthesis and SAR Studies of Novel and Potent Dipeptidyl Peptidase 4 Inhibitors
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 1, 页码: 115-120
作者:
Luo, Na
;
Fang, Xiaoyu
;
Su, Mingbo
;
Zhang, Xinwen
;
Li, Dan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/03/21
Type II diabetes
Dipeptidyl peptidase IV
Inhibitors
Molecular docking
Structure‐ activity relationship
Divalent tranylcypromine derivative as lysine-specific demethylase 1 inhibitor
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2021, 页码: 8
作者:
Sun, Yin
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/05/24
Divalent tranylcypromine
LSD1 inhibitor
MV4-11 antiproliferative activity
CD86 mRNA expression
Linker
Selectivity
Category, process, and recommendation of design in an interactive evolutionary computation interior design experiment: a data-driven study
期刊论文
OAI收割
AI EDAM-ARTIFICIAL INTELLIGENCE FOR ENGINEERING DESIGN ANALYSIS AND MANUFACTURING, 2020, 卷号: 34, 期号: 2, 页码: 233-247
作者:
Huang, Weixin
;
Su, Xia
;
Wu, Mingbo
;
Yang, Lijing
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/07/09
Clustering
color combination
design experiment
interactive evolutionary computation
recommendation system
Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 844-847
作者:
Wang, Xiaowen
;
Su, Mingbo
;
Li, You
;
Liu, Tongchao
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
LSD1 inhibitor
Tranylcypromine
Menin-MLL1 protei n-protein interaction inhibitor
MV4-11 antiproliferative activity
Structure activity relationship