机构

• 上海药物研究所 [10]

采集方式

• OAI收割 [10]

内容类型

• 期刊论文 [10]

发表日期

• 2024 [6]
• 2021 [1]
• 2020 [2]
• 2019 [1]

学科主题

筛选

浏览/检索结果: 共10条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Radioactive ADME Demonstrates ARV-110's High Druggability Despite Low Oral Bioavailability 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 15 作者:  He, Yifei;  Zheng, Yuandong;  Zhu, Chenggu;  Lei, Peng;  Yu, Jinghua   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/09/26 Application of Electro-Activated Dissociation Fragmentation Technique to Identifying Glucuronidation and Oxidative Metabolism Sites of Vepdegestrant by Liquid Chromatography-High Resolution Mass Spectrometry 期刊论文  OAI收割 DRUG METABOLISM AND DISPOSITION, 2024, 卷号: 52, 期号: 7, 页码: 634-643 作者:  He, Yifei;  Hou, Pengyi;  Long, Zhimin;  Zheng, Yuandong;  Tang, Chongzhuang   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/11/26 IDENTIFYING ACCURATE METABOLISM SITES OF VEPDEGESTRANT USING NOVEL ELECTRON-ACTIVATED DISSOCIATION HIGHRESOLUTION MASS SPECTROMETRY 期刊论文  OAI收割 DRUG METABOLISM AND PHARMACOKINETICS, 2024, 卷号: 55, 页码: 1 作者:  He, Yifei;  Hou, Pengyi;  Long, Zhimin   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/10/21 AN OVERVIEW OF CDE TECHNICAL GUIDELINE FOR NONCLINICAL STUDY OF ADCS: IMPORTANCE AND STRATEGY OF STUDYING RELEASE OF PAYLOAD-CONTAINING COMPONENTS FROM ADC AND THEIR FURTHER METABOLISM 期刊论文  OAI收割 DRUG METABOLISM AND PHARMACOKINETICS, 2024, 卷号: 55, 页码: 1 作者:  Tang, Chongzhuang;  Li, Zhiqiang;  He, Yifei;  Li, Linwei;  Diao, Xingxing   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/10/21 Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11 作者:  Wang, Weiqiang;  Chen, Chong;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong   |  收藏  |  浏览/下载：36/0  |  提交时间：2024/01/16 LN005  Metabolism  Peptide -drug conjugates  UHPLC-HRMS  Doxorubicin   Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS 期刊论文  OAI收割 XENOBIOTICA, 2024, 页码: 9 作者:  Yuan, Yali;  Wang, Weiqiang;  Luo, Jing   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/02/19 peptide-drug conjugate  PDC  LN005  metabolite identification  liver S9s   Metabolic Activation of Retrorsine may Disrupt Bile Acid Homeostasis in Mice through the Nrf2 Pathway 期刊论文  OAI收割 CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 11, 页码: 870-881 作者:  Pang, Xiaoyan;  Tang, Chongzhuang;  Cao, Peng;  Zhou, Lei;  Chen, Xiaoyan   |  收藏  |  浏览/下载：42/0  |  提交时间：2022/06/15 Retrorsine  bile acid  oxidative stress  reactive metabolite  transporter  Nrf2   Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability 期刊论文  OAI收割 BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 9 作者:  Qiu, Yanan;  Tang, Chongzhuang;  Li, Ranran;  Cao, Sumin;  Zhang, Yuqiang   |  收藏  |  浏览/下载：53/0  |  提交时间：2020/12/24 LC-MS  MS  N-oxide  stability  sutetinib   Qualitative and quantitative determination of anaprazole and its major metabolites in human plasma 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 183, 页码: 10 作者:  Tang, Chongzhuang;  Li, Liang;  Ma, Xifeng;  Wang, Jin;  Chen, Bo   |  收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01 Metabolite identification  LC-MS/MS  UPLC-UV/Q-TOF  Anaprazole   Mechanism of Reductive Metabolism and Chiral Inversion of Proton Pump Inhibitors 期刊论文  OAI收割 DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 6, 页码: 657-664 作者:  Tang, Chongzhuang;  Chen, Zhaoqiang;  Dai, Xiaojian;  Zhu, Weiliang;  Zhong, Dafang   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01