机构

• 上海药物研究所 [29]
• 植物研究所 [5]
• 新疆理化技术研究所 [4]
• 中国科学院大学 [1]

采集方式

• OAI收割 [38]
• iSwitch采集 [1]

内容类型

• 期刊论文 [39]

发表日期

• 2025 [3]
• 2024 [1]
• 2023 [2]
• 2021 [9]
• 2020 [3]
• 2019 [3]
• 更多

学科主题

• Agronomy [4]
• Water Reso... [2]
• Agricultur... [1]
• Plant Scie... [1]

筛选

浏览/检索结果: 共39条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20 作者:  Zheng, Fuqiang;  Hu, Zhengtao;  Chen, Hai;  Cheng, Jiaxin;  Hou, Qiongqiong   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/06/23 Heterocycle-fused phenylcyclohexylamines  Multi-target antagonists  NMDAR  Monoamine transporter  Antidepressants   Design and Development of a Novel Oral 4′-Fluorouridine Double Prodrug VV261 against SFTSV 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 9, 页码: 9811-9826 作者:  Cheng, Yong;  Zheng, Wei;  Dong, Xinru;  Sun, Tengxiao;  Xu, Mengwei   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/06/23 Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22 作者:  Guma, Samuel Desta;  Zhou, Zhaoyin;  Song, Kang;  Yang, Feipu;  Suo, Jin   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/12/11 SARS-CoV-2  3CL pro inhibitors  Peptidomimetics  Spiropyrrolidine derivatives   Combination of miR159 Mimics and Irinotecan Utilizing Lipid Nanoparticles for Enhanced Treatment of Colorectal Cancer 期刊论文  OAI收割 PHARMACEUTICS, 2024, 卷号: 16, 期号: 4, 页码: 18 作者:  Yang, Rulei;  Liu, Yiran;  Yang, Ning;  Zhang, Tian;  Hou, Jiazhen   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/05/31 colorectal cancer  plant-derived miR159  irinotecan  lipid nanoparticle   Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2 期刊论文  OAI收割 Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 5, 页码: 2384-2391 作者:  Xu, Zhijian;  Shi, Danrong;  Han, Jianbao   |  收藏  |  浏览/下载：42/0  |  提交时间：2024/03/27 Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221 作者:  He Yifei;  Liu Yin;  Yu Jinghua;  Cheng Huan;  Odilov Abdullajon   |  收藏  |  浏览/下载：27/0  |  提交时间：2023/05/22 TPN171  14CTPN171  PDE5 inhibitor  pulmonary arterial hypertension  healthy volunteers  pharmacokinetics  metabolite identification  mass balance   Facile and Cost-Effective Route for the Synthesis of Simmerafil 期刊论文  OAI收割 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2432-2437 作者:  Odilov, Abdullajon;  Liu, Yin;  Hu, Tianwen;  Jiang, Xiangrui;  Suo, Jin   |  收藏  |  浏览/下载：51/0  |  提交时间：2022/01/18 simmerafil  PDE5 inhibitor  salicylamide  synthesis   Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2 期刊论文  OAI收割 CELL RESEARCH, 2021, 页码: 3 作者:  Xie, Yuanchao;  Yin, Wanchao;  Zhang, Yumin;  Shang, Weijuan;  Wang, Zhen   |  收藏  |  浏览/下载：91/0  |  提交时间：2021/11/04 Weinreb Amide Approach to the Practical Synthesis of a Key Remdesivir Intermediate 期刊论文  OAI收割 JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 7, 页码: 5065-5072 作者:  Xie, Yuanchao;  Hu, Tianwen;  Zhang, Yan;  Wei, Daibao;  Zheng, Wei   |  收藏  |  浏览/下载：36/0  |  提交时间：2021/08/17 A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects 期刊论文  OAI收割 DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15, 页码: 2947-2959 作者:  Qian, Hongjie;  Chen, Qian;  Lang, Liyu;  Zou, Yang;  Pu, Huahua   |  收藏  |  浏览/下载：31/0  |  提交时间：2021/08/17 TPN171H  PDE5 inhibitor  safety  pharmacokinetics  food effect  healthy subjects