机构

• 上海药物研究所 [12]
• 地质与地球物理研究所 [1]
• 中国科学院大学 [1]
• 西安光学精密机械研究... [1]

采集方式

• OAI收割 [14]
• iSwitch采集 [1]

内容类型

• 期刊论文 [14]
• 会议论文 [1]

发表日期

• 2024 [3]
• 2023 [2]
• 2022 [2]
• 2019 [3]
• 2017 [2]
• 2016 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共15条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of Novel Pyrimidine-Based Derivatives as Nav1.2 Inhibitors with Efficacy in Mouse Models of Epilepsy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12912-12931 作者:  He, Guoxue;  Zheng, Yueming;  Chang, Shunzhen;  Wang, Long;  Yang, Xiaohao   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/09/26 Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2024, 页码: 29 作者:  Zhou, Xiaoyu;  Zhao, Cheng;  Xu, Haiyan;  Xu, Yixiang;  Zhan, Li   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/03/25 An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG 期刊论文  OAI收割 BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14 作者:  Liu, Zhipei;  Wang, Feng;  Yuan, Hui;  Tian, Fuyun;  Yang, Chuanyan   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/03/13 hERG  K525N  Gating Polarity  Voltage-Sensing Domain  LQT2   Design, Synthesis and Bioactivity of [3.3.3]Propellane-Based Voltage-Gated Calcium Channel alpha 2 delta Subunit Ligands 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 6, 页码: 2226-2238 作者:  He Jinyan;  Tian Fuyun;  Wu Qingqing;  Zheng Yueming;  Chen Yuting   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/10/17 propellane  voltage-gated calcium channel  alpha 2 delta subunit  synthesis  bioactivity  structure-activity relationship   Characterization of the role of TMEM175 in an in vitro lysosomal H+ fluxes model 期刊论文  OAI收割 FEBS JOURNAL, 2023, 页码: 19 作者:  Yang, Chuanyan;  Tian, Fuyun;  Hu, Mei;  Kang, Chunlan;  Ping, Meixuan   |  收藏  |  浏览/下载：69/0  |  提交时间：2023/10/17 glycocalyx  H+ leak  lysosome acidification  proton channel  TMEM175   Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel alpha 2 delta ligands for the treatment of chronic neuropathic pain 期刊论文  OAI收割 MEDICINAL CHEMISTRY RESEARCH, 2022, 页码: 26 作者:  Zhang, Yuanwen;  Zheng, Yueming;  Wu, Qingqing;  Tian, Fuyun;  Ma, Chuanjun   |  收藏  |  浏览/下载：38/0  |  提交时间：2023/04/10 Voltage-gated calcium channel  alpha 2 delta subunit  gamma-aminobutyric acid  Mirogabalin  Neuropathic pain  Structure-activity relationship   Epilepsy phenotype and response to KCNQ openers in mice harboring the Kcnq2 R207W voltage-sensor mutation 期刊论文  OAI收割 NEUROBIOLOGY OF DISEASE, 2022, 卷号: 174, 页码: 10 作者:  Tian, Fuyun;  Cao, Birong;  Xu, Haiyan;  Zhan, Li;  Nan, Fajun   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/12/13 KCNQ2  Epilepsy  Mouse model  HN37 (pynegabine)   Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models 期刊论文  OAI收割 SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12 作者:  Liao, Ping;  Qiu, Yunguang;  Mo, Yiqing;  Fu, Jie;  Song, Zhenpeng   |  收藏  |  浏览/下载：52/0  |  提交时间：2020/07/01 A Small-Molecule Compound Selectively Activates K2P Channel TASK-3 by Acting at Two Distant Clusters of Residues 期刊论文  OAI收割 MOLECULAR PHARMACOLOGY, 2019, 卷号: 96, 期号: 1, 页码: 26-35 作者:  Tian, Fuyun;  Qiu, Yunguang;  Lan, Xi;  Li, Min;  Yang, Huaiyu   |  收藏  |  浏览/下载：25/0  |  提交时间：2020/07/01 Crustal P wave velocity structure beneath the SE margin of the Tibetan Check for Plateau from Deep Seismic Sounding results 期刊论文  OAI收割 TECTONOPHYSICS, 2019, 卷号: 755, 页码: 109-126 作者:  Lin, Jiyan;  Mooney, Walter D.;  Wang, Fuyun;  Duan, Yonghong;  Tian, Xiaofeng   |  收藏  |  浏览/下载：72/0  |  提交时间：2019/05/20 SE margin Tibet  Deep Seismic Sounding  P-wave velocity structure  Lower crustal flow  Deep processes