中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [4]
大连化学物理研究所 [3]
中国科学院大学 [1]
采集方式
OAI收割 [7]
iSwitch采集 [1]
内容类型
期刊论文 [8]
发表日期
2021 [1]
2017 [1]
2016 [2]
2011 [1]
2009 [1]
2008 [2]
更多
学科主题
筛选
浏览/检索结果:
共8条,第1-8条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
OAI收割
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61
作者:
Li, Xin
;
Yang, Changyong
;
Wan, Hong
;
Zhang, Ge
;
Feng, Jun
  |  
收藏
  |  
浏览/下载:146/0
  |  
提交时间:2019/01/08
Pyrotinib
HER2-postive breast cancer
Irreversible EGFR/HER2 dual tyrosine kinase
inhibitor
Preclinical
Clinical
Safety
Drug metabolism
Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry
期刊论文
iSwitch采集
Journal of chromatography b-analytical technologies in the biomedical and life sciences, 2016, 卷号: 1033, 页码: 117-127
作者:
Zhu, Yunting
;
Li, Liang
;
Zhang, Ge
;
Wan, Hong
;
Yang, Changyong
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/05/09
Pyrotinib
Uplc/q-tof ms
Metabolism
Human
Cyp3a4
Drug-drug interaction
Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1033, 页码: 117-127
作者:
Zhu, Yunting
;
Li, Liang
;
Zhang, Ge
;
Wan, Hong
;
Yang, Changyong
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Pyrotinib
UPLC/Q-TOF MS
Metabolism
Human
CYP3A4
Drug-drug interaction
LC-MS/MS determination of tizanidine in human plasma
期刊论文
OAI收割
Chinese Journal of Pharmaceutical Analysis, 2011, 卷号: 31, 期号: 8, 页码: 1435-1439
作者:
WAN Mimi
;
ZHAN Yan
;
CHEN Xiaoyan
;
ZHANG Yifan
;
ZHONG Dafang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
tizanidine
imidazoline derivative
liquid chromatography
mass spectrometry
pharmacokinetics
A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry
期刊论文
OAI收割
molecular biosystems, 2009, 卷号: 5, 期号: 8, 页码: 868-876
作者:
Yin, Peiyuan
;
Wan, Dafang
;
Zhao, Chunxia
;
Chen, Jing
;
Zhao, Xinjie
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2010/11/30
Analysis of acetylcholine, choline and butyrobetaine in human liver tissues by hydrophilic interaction liquid chromatography-tandem mass spectrometry
期刊论文
OAI收割
journal of pharmaceutical and biomedical analysis, 2008, 卷号: 47, 期号: 4-5, 页码: 870-875
作者:
Wang, Yuan
;
Wang, Tao
;
Shi, Xianzhe
;
Wan, Dafang
;
Zhang, Pingping
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2015/11/12
HILIC
tandem mass spectrometry
acetylcholine
choline
butyrobetaine
tissue
liver
Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography
期刊论文
OAI收割
proteomics, 2008, 卷号: 8, 期号: 7, 页码: 1346-1361
作者:
Han, Guanghui
;
Ye, Mingliang
;
Zhou, Houjiang
;
Jiang, Xinning
;
Feng, Shun
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2010/11/30
human liver
phosphopeptide validation
phosphoproteome analysis
SAX