中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [114]
大连化学物理研究所 [12]
西北高原生物研究所 [11]
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期刊论文 [204]
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Relief of loperamide-induced constipation by peptidic and small molecule RXFP4 agonists in mice
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 237, 页码: 12
作者:
Yan, Shiyu
;
Chen, Yan
;
Wang, Jiang
;
Wang, Qiuying
;
Zhou, Qingtong
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
RXFP4
INSL5
Agonist
Constipation
Colonic motility
Enriched pathways in gut microbiome predict response to immune checkpoint inhibitor treatment across demographic regions and various cancer types
期刊论文
OAI收割
ISCIENCE, 2025, 卷号: 28, 期号: 4, 页码: 21
作者:
Cai, Xunhui
;
Cho, Jennifer Y.
;
Chen, Lijun
;
Liu, Yufeng
;
Ji, Fenghu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/05/27
Molecular mechanisms of urate transport by the native human URAT1 and its inhibition by anti-gout drugs
期刊论文
OAI收割
CELL DISCOVERY, 2025, 卷号: 11, 期号: 1, 页码: 12
作者:
Wu, Canrong
;
Zhang, Chao
;
Jin, Sanshan
;
Wang, James Jiqi
;
Dai, Antao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/05/27
Computation-Enabled Structure-Based Discovery of Potent Binders for Small-Molecule Aptamers
期刊论文
OAI收割
JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2025, 卷号: 21, 期号: 6, 页码: 3216-3230
作者:
Zhou, Qingtong
;
Zhang, Zheng
;
Gao, Ling
;
Li, Guanyi
;
Zhang, Yue
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/04/24
Weight Loss Blockbuster Development: A Role for Unimolecular Polypharmacology
期刊论文
OAI收割
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2025, 卷号: 65, 页码: 191-213
作者:
Zhou, Qingtong
;
Li, Guanyi
;
Hang, Kaini
;
Li, Jie
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
overweight
glucagon-like peptide-1 receptor
unimolecular
polypharmacology
tirzepatide
retatrutide
metabolic diseases
Talaketides A-G, linear polyketides with prostate cancer cytotoxic activity from the mangrove sediment-derived fungus Talaromyces sp. SCSIO 41027
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2024, 卷号: 22, 期号: 11, 页码: 1047-1056
作者:
Chen, Chunmei
;
Wang, Xueni
;
Fang, Wenxuan
;
Liang, Jiaqi
;
Cai, Jian
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/12/11
[KEY WORDS] Mangrove sediment-derived fungus
Talaromyces sp.
Linear polyketides
Cytotoxicity
Prostate cancer.
Molecular basis of enhanced GLP-1 signaling mediated by GLP-1(9-36) in conjunction with LSN3318839
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 5069-5073
作者:
Li, Jie
;
Li, Guanyi
;
Mai, Yiting
;
Liu, Xiao
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/01/06
GLP-1(9-36)
Cryo-electron microscopy
Metabolite
Allosteric modulation
Single-cell mapping of peripheral blood mononuclear cells reveals key transcriptomic changes favoring coronary artery lesion in IVIG-resistant Kawasaki disease
期刊论文
OAI收割
HELIYON, 2024, 卷号: 10, 期号: 18, 页码: 15
作者:
Zheng, Yuanzheng
;
Zhou, Yan
;
Zhu, Di
;
Fu, Xing
;
Xie, Cao
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/10/21
Kawasaki disease
IVIG-Resistant
Single cell RNA-Sequencing
Coronary artery lesion
Single-cell sequencing reveals the heterogeneity of pancreatic neuroendocrine tumors under genomic instability and histological grading
期刊论文
OAI收割
ISCIENCE, 2024, 卷号: 27, 期号: 9, 页码: 18
作者:
Ye, Zeng
;
Zhou, Yan
;
Hu, Yuheng
;
Li, Qiang
;
Xu, Zijin
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/11/05
tumor cells
CNV neutral tumor cells
neuroendocrine cells
profile
Absence of PNET formation and normal longevity in a mouse model of Mahvash disease
期刊论文
OAI收割
HELIYON, 2024, 卷号: 10, 期号: 15, 页码: 13
作者:
Xu, Yingna
;
Liu, Qiaofeng
;
Chen, Chuan-Wei
;
Wang, Qiuying
;
Du, Tianyuan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/09/26
Glucagon
Glucagon receptor
Amino acid
Metabolism
Mahvash disease