中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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过程工程研究所 [29]
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期刊论文 [63]
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PEGylation of Dipeptide Linker Improves Therapeutic Index and Pharmacokinetics of Antibody-Drug Conjugates
期刊论文
OAI收割
BIOCONJUGATE CHEMISTRY, 2025, 页码: 11
作者:
Long, Jing
;
Shao, Ting
;
Wang, Yongmei
;
Chen, Tianzhi
;
Chen, Yuning
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
Simultaneous Quantification of Total Antibody and Conjugated Payload for DS001 in Rat Serum Using a Hybrid Immuno-Capture LC-MS/MS
期刊论文
OAI收割
AAPS JOURNAL, 2025, 卷号: 27, 期号: 1, 页码: 13
作者:
Yu, Xiong
;
Li, Weiqiang
;
Huang, Wensi
;
Xiao, Bo
;
Long, Jing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
ADC
LC-MS/MS
payload
simultaneous quantification
total antibody
Comparison of "framework Shuffling" and "CDR Grafting" in humanization of a PD-1 murine antibody
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 16
作者:
Wang, Yongmei
;
Chen, Yi-Li
;
Xu, Hui
;
Rana, Gul E.
;
Tan, Xiaorong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/09/26
antibody humanization
programmed death-1
FR shuffling
CDR grafting
immunogenicity
Dynamics of Water Sighting and Injection Mechanisms in Fishbone Branch Wells in Bottom Water Reservoirs
期刊论文
OAI收割
JOURNAL OF ENERGY RESOURCES TECHNOLOGY-TRANSACTIONS OF THE ASME, 2024, 卷号: 146, 期号: 7, 页码: 8
作者:
Zhang, Guoqing
;
Cui, Chunxue
;
Zhou, Zhijun
;
Wang, Juan
;
Zhang, Jian
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/06/17
bottom water reservoir
water cresting & coning
fishbone branch well
breakthrough time
waterflood adjustment
Numerical Simulation of Oil Displacement in Complex Fault Block Reservoir
期刊论文
OAI收割
CHEMISTRY AND TECHNOLOGY OF FUELS AND OILS, 2023, 卷号: 59, 期号: 2, 页码: 332
作者:
Lv, Yanxin
;
Wang, Guifeng
;
Fang, Xiaoyu
;
Li, Xushen
;
Fu, Yanzhao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/08/02
TOUGH2
complicated fault block reservoir
well-patterns
injection-production pressure difference
Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 659, 页码: 10-19
作者:
Zhu,Yiying
;
Zhao,Zhangxun
;
Xue,Minggao
;
Wang,Dan
;
Su,Guifeng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/07/22
Ciclopirox olamine
Natural killer cells
NKG2D ligands
Immunotherapy
LIGANDS
RECEPTOR
GROWTH
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:
Yang,Qihong
;
Qin,Tong
;
An,Tao
;
Wu,Hongna
;
Xu,Gang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/07/30
PORCN inhibitor
WHN-88
Palmitoylation
Wnt-driven cancers
SIGNALING PATHWAY
PORCUPINE
STEM
GENE
ACYLTRANSFERASE
MUTATIONS
POLARITY
PROTEIN
RNF43
MICE
Enzyme-linked immunosorbent assays for quantification of MMAE-conjugated ADCs and total antibodies in cynomolgus monkey sera
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2022, 卷号: 12, 期号: 4, 页码: 645-652
作者:
Pei, Min
;
Liu, Tingting
;
Ouyang, Lu
;
Sun, Jianhua
;
Deng, Xiaojie
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2022/11/11
Monomethyl auristatin E
Antibody-drug conjugates
Pharmacokinetics
Trophoblast cell surface antigen 2
Development and characterization of anti-HPV16 monoclonal antibodies for assembly of an HPV16 detection kit
期刊论文
OAI收割
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 2022, 页码: 9
作者:
Liu, Yuying
;
Zhang, Yao
;
Zhang, Guifeng
;
Yang, Zengmin
;
Wang, Yan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/02/24
ELISA kit
HPV vaccine
HPV16
monoclonal antibody
Analgesic effects of nerve growth factor-directed monoclonal antibody on diabetic neuralgia in an animal model
期刊论文
OAI收割
FEBS OPEN BIO, 2022, 页码: 11
作者:
Dong, Xingchen
;
Li, Huanhuan
;
Pei, Min
;
Tan, Jie
;
Chen, Ganjun
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/06/15
diabetic neuralgia
neuropathic pain
nerve growth factor
monoclonal antibody
analgesia