中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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自动化研究所 [68]
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Applications of innovative synthetic strategies in anticancer drug discovery: The driving force of new chemical reactions
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 119, 页码: 36
作者:
Wang, Han
;
Ma, Xiaolong
;
Sun, Longkang
;
Bi, Tongyu
;
Yang, Weibo
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2025/04/01
Synthetic methodologies
Medicinal chemistry
New chemical reactions
Anticancer drug discovery
Tailoring nanovectors for optimal neoantigen vaccine efficacy
期刊论文
OAI收割
JOURNAL OF MATERIALS CHEMISTRY B, 2025, 卷号: 13, 期号: 13, 页码: 4045-4058
作者:
Zheng, Youshi
;
Wang, Bing
;
Cai, Zhixiong
;
Lai, Zisen
;
Yu, Haijun
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
A Study of Subsurface Convection Zones of Fast Rotating Massive Stars
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 3, 页码: 035002
作者:
He, Xiaolong
;
Lu, Guoliang
;
Zhu, Chunhua
;
Li, Lin
;
Liu, Helei
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/17
stars: early-type
stars: evolution
stars: massive
stars: rotation
convection
A prodrug nanodevice co-delivering docetaxel and ROR1 siRNA for enhanced triple negative breast cancer therapy
期刊论文
OAI收割
ACTA BIOMATERIALIA, 2025, 卷号: 193, 页码: 498-513
作者:
Yin, Lixuan
;
Fu, Zirang
;
Wang, Mengmeng
;
Liu, Bo
;
Sun, Xujie
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/04/01
Triple-negative breast cancer
Docetaxel
Prodrug nanoparticle
ROR1 siRNA
pH responsive
Field and numerical investigation of groundwater flow and dissolved inorganic nitrogen (DIN) dynamics in a sandy nearshore aquifer
期刊论文
OAI收割
JOURNAL OF HYDROLOGY, 2025, 卷号: 646, 页码: 10
作者:
Wang, Zhenyan
;
Robinson, Clare E.
;
Geng, Xiaolong
;
Xiao, Kai
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/01/10
Submarine groundwater discharge
Numerical modeling
Dissolved inorganic nitrogen
Sandy nearshore aquifer
Intertidal zone
Advanced vat photopolymerization 3D printing of silicone rubber with high precision and superior stability
期刊论文
OAI收割
International Journal of Extreme Manufacturing, 2024, 卷号: 7, 期号: 2
作者:
Ji,Zhongying
;
Xu,Bingang
;
Su,Zhiyong
;
Wang,Xiaochen
;
Lyu,Yang
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/01/20
3D printing
silicone rubber
high printing resolution
pneumatic actuator
Targeted inhibition of Gus-expressing Enterococcus faecalis to promote intestinal stem cell and epithelial renovation contributes to the relief of irinotecan chemotoxicity by dehydrodiisoeugenol
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5286-5304
作者:
Gao, Ruiyang
;
Yue, Bei
;
Lv, Cheng
;
Geng, Xiaolong
;
Yu, Zhilun
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
Irinotecan
Intestinal mucositis
b-Glucuronidase
Enterococcus faecalis
Intestinal stem cells
Epithelial regeneration
bacteria-host irinotecan axis
Dehydrodiisoeugenol
miCGR: interpretable deep neural network for predicting both site-level and gene-level functional targets of microRNA
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 26, 期号: 1, 页码: 13
作者:
Wu, Xiaolong
;
Zhang, Lehan
;
Tong, Xiaochu
;
Wang, Yitian
;
Zhang, Zimei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/12/25
MicroRNA
target prediction
chaos game representation
deep learning
convolutional neural network
Ginkgetin Alleviates Inflammation and Senescence by Targeting STING
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 15
作者:
Liu, Yadan
;
Ye, Jialin
;
Fan, Zisheng
;
Wu, Xiaolong
;
Zhang, Yinghui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/12/16
cGAS-STING signaling
Ginkgetin
senescence
STING inhibitor
target identification
Comparative evaluation of machine learning models for assessment of seabed liquefaction using finite element data
期刊论文
OAI收割
FRONTIERS IN MARINE SCIENCE, 2024, 卷号: 11, 页码: 15
作者:
Du, Xing
;
Song, Yupeng
;
Wang, Dong
;
He, Kunpeng
;
Chi, Wanqing
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/27
submarine pipelines
gradient boosting
support vector machine
machine learning
wave-current coupling