中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
合肥物质科学研究院 [64]
上海药物研究所 [8]
西安光学精密机械研究... [5]
寒区旱区环境与工程研... [3]
宁波材料技术与工程研... [1]
广州能源研究所 [1]
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期刊论文 [81]
会议论文 [1]
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2025 [1]
2024 [4]
2023 [1]
2022 [6]
2021 [9]
2020 [7]
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核科学技术 [2]
生物学 [2]
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Conformational analysis of soticlestat, an inhibitor of CYP46A1 (CH24H), and its derivatives by variable-temperature nmr and computational methods
期刊论文
OAI收割
STRUCTURAL CHEMISTRY, 2025, 页码: 25
作者:
Huang, Wenqian
;
Hu, Xinwei
;
Lin, Xiaotong
;
Khan, Maaz
;
Qian, Chunli
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Atropisomerism
Axial chirality
Soticlestat
Variable-temperature NMR
Molecular mechanics
Quantum mechanics
Rationally designed catalytic nanoplatform for enhanced chemoimmunotherapy via deploying endogenous plus exogenous copper and remodeling tumor microenvironment
期刊论文
OAI收割
JOURNAL OF NANOBIOTECHNOLOGY, 2024, 卷号: 22
作者:
Sun, Daxi
;
Yu, Liting
;
Wang, Gang
;
Xu, Yuxue
;
Wang, Peng
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/11/20
Copper peroxide
Chemodynamic therapy
Chloroquine
Autophagy
Immunogenic cell death, MHC-II
Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 17
作者:
Zhang, Tao
;
Pan, Zilu
;
Gao, Jing
;
Wu, Qingqing
;
Bai, Gang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/10/21
Design, Synthesis and Bioactivity of NYX-2925
L
-Proline Derivatives as
N
-Methyl-D-aspartate (NMDA) Receptor Partial Agonists
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 4, 页码: 1247-1263
作者:
Wu Youjin
;
Jin Zhengsheng
;
Liu Yongjia
;
Huang Wenqian
;
Zhao Guilong
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/08/22
N-methyl-D-aspartate (NMDA) receptor
partial agonist
NYX-2925
synthesis
bioactivity
Regioselective Deacetylation of Peracetylated Deoxy-
C
-glycopyranosides by Boron Trichloride (BCl
3
)
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2024, 页码: 16
作者:
Chen, Shuangyuan
;
Wei, Feifei
;
Cheng, Xinqiang
;
Luo, Ying
;
Meng, Fancui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/05/07
Design, Synthesis and Bioactivity of [3.3.3]Propellane-Based Voltage-Gated Calcium Channel alpha 2 delta Subunit Ligands
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 6, 页码: 2226-2238
作者:
He Jinyan
;
Tian Fuyun
;
Wu Qingqing
;
Zheng Yueming
;
Chen Yuting
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/10/17
propellane
voltage-gated calcium channel
alpha 2 delta subunit
synthesis
bioactivity
structure-activity relationship
Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel alpha 2 delta ligands for the treatment of chronic neuropathic pain
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2022, 页码: 26
作者:
Zhang, Yuanwen
;
Zheng, Yueming
;
Wu, Qingqing
;
Tian, Fuyun
;
Ma, Chuanjun
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/04/10
Voltage-gated calcium channel
alpha 2 delta subunit
gamma-aminobutyric acid
Mirogabalin
Neuropathic pain
Structure-activity relationship
PDGF-B conjugating mesoporous IO/GdO nanocomposites for accurate diagnosis of orthotopic prostatic cancer through T-1-T-2 dual-modal MRI contrast enhancement
期刊论文
OAI收割
MATERIALS TODAY ADVANCES, 2022, 卷号: 16
作者:
Li, Qingdong
;
Xiao, Jianmin
;
Zhang, Caiyun
;
Wang, Peng
;
Li, Wenling
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/12/22
IO
GdO nanocomposite
T1
T2 dual modal MRI
Orthotopic prostate cancer
Accurate diagnosis
Transition-metal-doped hydrophilic ultrasmall iron oxide modulates MRI contrast performance for accurate diagnosis of orthotopic prostate cancer
期刊论文
OAI收割
JOURNAL OF MATERIALS CHEMISTRY B, 2022, 卷号: 10
作者:
Xie, Wenteng
;
Gan, Yuehao
;
Zhang, Ya'nan
;
Wang, Peng
;
Zhang, Jia
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/12/23
Atomically precise multi-domain GdxFe3-xO4 nanoclusters with modulated contrast properties for T-2-weighted magnetic resonance imaging of early orthotopic cancer
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2022, 卷号: 429
作者:
Gan, Yuehao
;
Zhang, Jia
;
Lei, Shulai
;
Yan, Miao
;
Xie, Wenteng
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2022/01/10
Gd doping
Magnetic iron oxide nanoclusters
Atomically precise
MRI
T-2-weighted contrast agents