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Advancing active compound discovery for novel drug targets: insights from AI-driven approaches
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12
作者:
Wang, Xing-you
;
Chen, Yang
;
Li, Yu-fan
;
Wei, Chao-yang
;
Liu, Meng-ya
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/08/20
AI-driven drug discovery
novel drug targets
molecular design
ligand exploration
phenotypic drug discovery
undruggable targets
ATR-FTIR Coupled With Machine Learning Provides a Fast Method for Identifying and Distinguishing 55 Varieties of Fruit-Derived Medicinal Materials
期刊论文
OAI收割
PHYTOCHEMICAL ANALYSIS, 2025, 页码: 13
作者:
Zhao, Wen-jie
;
An, Ya-ling
;
Song, Chun-qian
;
Huang, Yu-shi
;
Zhang, Li-jie
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
ATR-FTIR
fruit-derived medicinal materials
machine learning
species discrimination
Analysis of ligustrazine covalent cyclodextrin frameworks in bioinformatics and network pharmacology-based acute lung injury treatment
期刊论文
OAI收割
ARABIAN JOURNAL OF CHEMISTRY, 2025, 卷号: 18, 期号: 4, 页码: 12
作者:
Wu, Di
;
Wang, Xiao Le
;
Jia, Yu
;
He, Si Yu
;
Gao, Ya Ting
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Acute lung injury
Bioinformatics
Covalent cyclodextrin frameworks
Ligustrazine
Pulmonary drug delivery
A holistic strategy for the in-depth discrimination and authentication of 16 citrus herbs and associated commercial products based on machine learning techniques and non-targeted metabolomics
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2025, 卷号: 1745, 页码: 12
作者:
Huang, Yu-shi
;
An, Ya-ling
;
Zheng, Yue-yuan
;
Zhao, Wen-jie
;
Song, Chun-qian
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2025/04/01
Citrus herbs
Discrimination
LC-MS
Machine learning
Differential markers
Concurrent inhibition of p300/CBP and FLT3 enhances cytotoxicity and overcomes resistance in acute myeloid leukemia
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 14
作者:
Chen, Yu-jun
;
Zhao, Yu
;
Yao, Ming-yue
;
Wang, Ya-fang
;
Ma, Ming
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/04/01
acute myeloid leukemia
FLT3
p300/CBP
quizartinib resistance
combination strategy
The synthesis and antileukemic activity of 5-substituted thiazolyl urea derivatives
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 115, 页码: 6
作者:
Peng, Cheng
;
Sheng, Li
;
Xu, Gao-Ya
;
Qi, Xiao-Lei
;
Zhou, Yu-Bo
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/12/25
Antileukemic
Thiazolyl
Urea
Synthesis
SAR
A sample of the Moon's far side retrieved by Chang'e-6 contains 2.83-billion-year-old basalt
期刊论文
OAI收割
SCIENCE, 2024, 卷号: 386, 期号: 6728, 页码: 1395-1399
作者:
Cui, Zexian
;
Yang, Qing
;
Zhang, Yan-Qiang
;
Wang, Chengyuan
;
Xian, Haiyang
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2025/04/01
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2025/04/01
Integration of ion mobility-quadrupole time-of-flight mass spectrometry and triple quadrupole-ion trap mass spectrometry coupled with ultra-high performance liquid chromatography for characterizing and quantitatively assay the saponins of
Panax
quinquefolius
flower
期刊论文
OAI收割
MICROCHEMICAL JOURNAL, 2024, 卷号: 207, 页码: 14
作者:
Wang, Yu
;
Hong, Li-li
;
Sun, Meng-xiao
;
Li, Xue
;
Zou, Ya-dan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/12/16
Panax quinquefolius flower
UHPLC/IM-QTOF-MS
UHPLC/QTrap-MS
Multi-component characterization
Quantitative assay
Nanoparticle attachment promotes nugget effect of Au-rich metallic melts in hydrothermal ore deposits
期刊论文
OAI收割
CONTRIBUTIONS TO MINERALOGY AND PETROLOGY, 2024, 卷号: 179, 期号: 12, 页码: 12
作者:
Fan, Gao-Hua
;
Li, Jian-Wei
;
Wu, Ya-Fei
;
Hu, Si-Yu
;
Deng, Xiao-Dong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/04/01
Gold accumulation
Bismuth melts
Three-step growth
Oriented attachment