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浏览/检索结果: 共337条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Structure-Based Discovery of a Series of Novel MAT2a Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2025, 页码: 5 作者:  Zhou, Yushan;  Wang, Li;  Ren, Ruyue;  Zhang, Junjie;  Huan, Xiajuan   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/05/27 MAT2a  MTAP  Synthetic lethality  Allosteric inhibitor  Structure-activity relationship   Design of Selective BRD4 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 18 作者:  Yang, Yueyue;  Liu, Hongli;  Yuan, Haoxing;  Lyu, Kaikai;  Zhong, Haiyang   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/04/01 Structure-Based Rational Design and Evaluation of BET-Aurora Kinase Dual-Inhibitors for Treatment of Cancers 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21 作者:  Lyu, Kaikai;  Ren, Ying;  Mou, Jie;  Yang, Yunfang;  Pan, Yaoyao   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/02/28 Design and development of a series of 4-(piperazin-1-yl)pyrimidines as irreversible menin inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 280, 页码: 20 作者:  Luo, Menglan;  Ye, Yunfei;  Tang, Lu;  Kan, Weijuan;  Chen, Lin   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/11/26 Menin  Covalent inhibitor  Antitumor  Degradation   FAPM: functional annotation of proteins using multimodal models beyond structural modeling 期刊论文  OAI收割 BIOINFORMATICS, 2024, 卷号: 40, 期号: 12, 页码: 12 作者:  Xiang, Wenkai;  Xiong, Zhaoping;  Chen, Huan;  Xiong, Jiacheng;  Zhang, Wei   |  收藏  |  浏览/下载：101/0  |  提交时间：2025/01/14 Optimization and Biological Evaluation of Novel 1H-Pyrrolo[2,3-c]pyridin Derivatives as Potent and Reversible Lysine Specific Demethylase 1 Inhibitors for the Treatment of Acute Myelogenous Leukemia 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 24, 页码: 22080-22103 作者:  Jiang, Hong;  Li, Cong;  Li, Na;  Sheng, Li;  Wang, Jingkai   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/01/14 Structural mechanism of human HCN1 hyperpolarization-activated channel inhibition by ivabradine 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 卷号: 300, 期号: 11, 页码: 9 作者:  Che, Tong;  Zhang, Wei;  Cheng, Xinyu;  Lv, Sijia;  Zhang, Minqing   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/11/26 Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7 (8H)-one derivatives as potent USP1 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18 作者:  Li, Hongrui;  Liu, Ben-Jin;  Xu, Jiahao;  Song, Shan-Shan;  Ba, Ruixian   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/08/22 USP1 inhibitor  Structure -activity relationships  Olaparib-resistant cell   Colossal Barocaloric Effect near Ambient Temperature in 1-Dodecanol under a Low Pressure 期刊论文  OAI收割 JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2024, 卷号: 15 作者:  Zhang, Zhipeng;  Xiong, Tingjiao;  Zhang, Zhao;  Li, Bing;  Tong, Peng   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/11/22 Remodeling tumor-associated macrophage for anti-cancer effects by rational design of irreversible inhibition of mitogen-activated protein kinase-activated protein kinase 2 期刊论文  OAI收割 MEDCOMM, 2024, 卷号: 5, 期号: 7, 页码: e634 作者:  Wang, Danyi;  Sun, Deqiao;  Wang, Xiaoyan;  Peng, Xia;  Ji, Yinchun   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/06/04 anti-tumor  irreversible inhibitor  kinase  macrophagemitogen-activated protein kinase-activated protein kinase 2 (MK2)