机构

• 上海药物研究所 [12]
• 新疆理化技术研究所 [1]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2025 [1]
• 2023 [3]
• 2022 [1]
• 2021 [4]
• 2020 [2]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共13条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16 作者:  Zeng, Gongruixue;  Xu, Gaoya;  Gao, Lixin;  Zheng, Xiaoli;  Chi, Xinglong   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/04/01 Proteasome inhibitors  Macrocycle  Stability  Anti-cancer activities   Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2023, 页码: 14 作者:  Deng, Minjie;  Gao, Yue;  Wang, Peipei;  Du, Wenjing;  Xu, Gaoya   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/02/19 Targeting C/EBP alpha overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18 作者:  Wang, Hanlin;  Luo, Guanghao;  Hu, Xiaobei;  Xu, Gaoya;  Wang, Tao   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 Design, Synthesis, and Biological Evaluation of 2-Aminothiazole Derivatives as Novel Checkpoint Kinase 1 (CHK1) Inhibitors 期刊论文  OAI收割 CHEMMEDCHEM, 2023, 页码: 19 作者:  Deng, Minjie;  Wang, Peipei;  Long, Xiubing;  Xu, Gaoya;  Wang, Chang   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 2-aminothiazole  CHK1 inhibitors  antiproliferation  hematologic malignancies  biological activity   Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 4335-4349 作者:  Li, Chunpu;  Su, Mingbo;  Zhu, Wei;  Kan, Weijuan;  Ge, Tianpeng   |  收藏  |  浏览/下载：44/0  |  提交时间：2022/06/15 Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity 期刊论文  OAI收割 PHYTOCHEMISTRY, 2021, 卷号: 187, 页码: 7 作者:  Kamoldinov, Khamidulla;  Li, Jun;  Eshbakova, Komila;  Sagdullaev, Shamansur;  Xu, Gaoya   |  收藏  |  浏览/下载：35/0  |  提交时间：2021/08/17 Ferula samarkandica Korovin  Apiaceae  Samarcandicins A-I  Sesquiterpene coumarin  Cytotoxity  MV-4-11 cell  Mino cell   Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia 期刊论文  OAI收割 CHEMMEDCHEM, 2021, 页码: 12 作者:  Jin, Tingting;  Wang, Peipei;  Long, Xiubing;  Jiang, Kailong;  Song, Pinrao   |  收藏  |  浏览/下载：133/0  |  提交时间：2021/05/24 CHK1 inhibitor  diaminopyrimidine  DNA damage response  oral bioavailability   Design, synthesis and biological evaluation of thioether-containing lenalidomide and pomalidomide derivatives with anti-multiple myeloma activity 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 13 作者:  Wang, Yuhong;  Mi, Tian;  Li, Yiming;  Kan, Weijuan;  Xu, Gaoya   |  收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 Lenalidomide  Multiple myeloma  MM.1S  Late-stage sulfuration   Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity 期刊论文  OAI收割 PHYTOCHEMISTRY, 2021, 卷号: 187, 期号: 7, 页码: 1-7 作者:  Kamoldinov, K (Kamoldinov, Khamidulla) 1 , 2;  Li, J (Li, Jun) 1 , 2;  Eshbakova, K (Eshbakova, Komila) 3;  Sagdullaev, S (Sagdullaev, Shamansur) 3;  Xu, GY (Xu, Gaoya) 4   |  收藏  |  浏览/下载：45/0  |  提交时间：2021/07/27 Ferula samarkandica KorovinApiaceaeSamarcandicins A-ISesquiterpene coumarinCytotoxityMV-4-11 cellMino cell   Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19 作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue   |  收藏  |  浏览/下载：58/0  |  提交时间：2020/12/21 Metabolic pathways  Isocitrate dehydrogenase 2  Conformational restriction  Macrocyclic derivatives  Inhibitors