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Chinese Academy of Sciences Institutional Repositories Grid
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期刊论文 [288]
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Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13
作者:
Wu, Feifei
;
Li, Huiyu
;
Li, Weiqiang
;
Zhang, Laishun
;
An, Qi
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/04/01
Optimization
Hematopoietic progenitor kinase 1
Inhibitor
Cancer immunotherapy
Nonlinear dynamic analysis and vibration reduction of two sandwich beams connected by a joint with clearance
期刊论文
OAI收割
MECHANICAL SYSTEMS AND SIGNAL PROCESSING, 2025, 卷号: 223, 页码: 24
作者:
Guo, Zhenkun
;
Jiang, Shuai
;
Shen, Yongjun
;
Jiang, Guoqing
;
Xiao, Boya
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/10/08
Interconnect sandwich beam
Equivalent joint model
Rayleigh-Ritz method
Clearance
Enhanced Antitumor Immunity of a Globo H-Based Vaccine Enabled by the Combination Adjuvants of 3D-MPL and QS-21
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 11
作者:
Ma, Wenjing
;
Xu, Zhuojia
;
Teng, Changcai
;
Cao, Chang
;
Wu, Ruixue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Carbohydrates
oligosaccharide synthesis
synthesis design
carbohydrate-based vaccines
immunological activity
Chemical profiling and comparative analysis of different parts of
Asarum
heterotropoides
using SPME-GC-QTOF-MS and LC- Orbitrap-MS
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 252, 页码: 9
作者:
Hu, Yun-shu
;
Zhang, Jian-qing
;
Xu, Meng
;
Yang, Huan-ya
;
Liu, Chun-xiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/26
Asari radix et rhizoma
A. heterotropoides
SPME-GC-MS
LC-Orbitrap-MS
Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Zhai, Lin-hui
;
Jia, Xing-long
;
Chen, Yu-lu
;
Liu, Mu-yin
;
Zhang, Jing-dan
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2024/12/25
colchicine
MLN4924
multi-omics analysis
phosphoproteomics
ubiquitinomics
kinase inhibitor
Cisplatin resistance-related transcriptome and methylome integration identifies PCDHB4 as a novel prognostic biomarker in small cell lung cancer
期刊论文
OAI收割
ISCIENCE, 2024, 卷号: 27
作者:
Zhu, Qizhi
;
Fu, Meng
;
Qi, Jian
;
Xu, Ziming
;
Wang, Yongguang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/11/22
Medcheck: a novel software for automated de-formulation of traditional Chinese medicine (TCM) prescriptions by liquid chromatography-mass spectrometry
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2024, 卷号: 14, 期号: 6, 页码: 3
作者:
Li, Xiao-lan
;
Zhang, Jian-qing
;
Li, Yun
;
Shen, Xuan-jing
;
Yang, Huan-ya
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/22
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
;
Xiang, Huaijiang
;
Meng, Huyan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
Space advanced technology demonstration satellite
期刊论文
OAI收割
Science China Technological Sciences, 2024, 卷号: 67, 期号: 1, 页码: 240-258
作者:
Zhang, XiaoFeng
;
Chen, Wen
;
Zhu, XiaoCheng
;
Meng, Na
;
He, JunWang
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/02/01
SATech-01
spacecraft design
scientific instruments
on-orbit performance
Combining Cd and Pb isotope analyses for heavy metal source apportionment in facility agricultural soils around typical urban and industrial areas
期刊论文
OAI收割
Journal of Hazardous Materials, 2024, 卷号: 466
作者:
Yafei Xia
;
Yuhui Liu
;
Tao Chen
;
Yudi Xu
;
Meng Qi
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/03/12