中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
生态环境研究中心 [7]
上海药物研究所 [6]
深圳先进技术研究院 [4]
地理科学与资源研究所 [4]
中国科学院大学 [4]
过程工程研究所 [3]
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OAI收割 [46]
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内容类型
期刊论文 [46]
专著 [2]
会议论文 [2]
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2024 [10]
2022 [1]
2021 [5]
2020 [5]
2019 [4]
2018 [9]
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学科主题
天文学 [1]
天文学::星系与宇宙... [1]
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Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:
Nie, Hui-Jun
;
Li, Ben-Fu
;
Sun, Jingya
;
Yuan, Yali
;
Zhang, Zhi-Gao
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/26
Triple-negative breast cancer
Targeting transcription regulation
Orally bioavailable degrader
PROTAC
Cyclin-dependent Kinase 9
Emerging Pollutants
期刊论文
OAI收割
PROGRESS IN CHEMISTRY, 2024, 卷号: 36, 期号: 11, 页码: 1607-1784
作者:
Wang, Yawei
;
Zhang, Qiurui
;
Yu, Nanyang
;
Wang, Yuan
;
Wei, Si
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/03
emerging pollutants
occurrence level
environmental behavior
ecological risks
control strategies
Discovery of Orally Bioavailable and Potent CDK9 Inhibitors for Targeting Transcription Regulation in Triple-Negative Breast Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 12, 页码: 10035-10056
作者:
Wang, Wen-Jing
;
Gao, Lixin
;
Wang, Simei
;
Huang, Wensi
;
Meng, Xin-Yu
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/20
A validated LC-MS/MS method for the quantitation of daratumumab in rat serum using rapid tryptic digestion without IgG purification and reduction
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 243, 页码: 8
作者:
Li, Weiqiang
;
Huang, Wensi
;
Yu, Xiong
;
Chen, Chong
;
Yuan, Yali
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/05/22
Daratumumab
LC-MS/MS
Surrogate peptide
Pharmacokinetics
Deep sea cold seeps are a sink for mercury and source for methylmercury
期刊论文
OAI收割
COMMUNICATIONS EARTH & ENVIRONMENT, 2024, 卷号: 5, 期号: 1, 页码: 10
作者:
Li, Jiwei
;
Dong, Xiyang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/10/21
Absorption, distribution, metabolism and excretion of linaprazan glurate in rats
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 242, 页码: 10
作者:
Zhang, Xinyue
;
Liu, Donghui
;
Lu, Ming
;
Yuan, Yali
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/07
Linaprazan glurate
[14C]linaprazan glurate
Linaprazan
ADME
Radio-labeling
P-CAB
Tracking the flows of Hg, As, Cd, Cr, and Pb in Chinese coal-fired industrial boilers
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2024, 卷号: 466, 页码: 13
作者:
Tong, Yali
;
Gao, Jiajia
;
Yue, Tao
;
Yuan, Yue
;
Tang, Yu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/05/06
Coal-fired industrial boilers (CFIBs)
Heavy metals (HMs)
Emission inventory
Waste inventory
Material flow
Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11
作者:
Wang, Weiqiang
;
Chen, Chong
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/01/16
LN005
Metabolism
Peptide -drug conjugates
UHPLC-HRMS
Doxorubicin
High-precision spatio-temporal variations and future perspectives of multiple air pollutant emissions from Chinese biomass-fired industrial boilers
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 907, 页码: 14
作者:
Yue, Tao
;
Tong, Yali
;
Gao, Jiajia
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/02
Biomass -fired industrial boiler (BFIB)
Air pollutants
Trace metals
Emission inventory
Spatio-temporal variation
Scenario projection
Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS
期刊论文
OAI收割
XENOBIOTICA, 2024, 页码: 9
作者:
Yuan, Yali
;
Wang, Weiqiang
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/02/19
peptide-drug conjugate
PDC
LN005
metabolite identification
liver S9s