中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
广州能源研究所 [2]
高能物理研究所 [1]
半导体研究所 [1]
采集方式
OAI收割 [13]
iSwitch采集 [1]
内容类型
期刊论文 [14]
发表日期
2020 [3]
2019 [3]
2018 [6]
2017 [2]
学科主题
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Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion
期刊论文
OAI收割
ADVANCED SCIENCE, 2020, 页码: 13
作者:
Sun, Zhongya
;
Zhang, Hao
;
Zhang, Yuanyuan
;
Liao, Liping
;
Zhou, Wen
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2020/07/01
anti-metastasis activities
crystal structures
inhibitors
novel pockets
rho family proteins
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10
作者:
Hou, Zeng
;
Min, Wenjian
;
Zhang, Rukang
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
Histone methylation
SET7
Small-molecule inhibitor
Virtual screening
Molecular probe
Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 3, 页码: 1337-1360
作者:
Yang, Yaxi
;
Zhang, Rukang
;
Li, Zhaojun
;
Mei, Lianghe
;
Wan, Shili
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 4, 页码: 638-645
作者:
Ye, Xiaoqing
;
Zhang, Rukang
;
Lian, Fulin
;
Zhang, Weiyao
;
Lu, Wenchao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
WDR5-MLL1 interaction
Leukemia
Small-molecule
High-throughput screening
Fluorescence polarization (FP)
Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening
期刊论文
OAI收割
RSC ADVANCES, 2019, 卷号: 9, 期号: 9, 页码: 4917-4924
作者:
Tao, Hongru
;
Wang, Jun
;
Lu, Wenchao
;
Zhang, Rukang
;
Xie, Yiqian
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
experimentalstudyonconversionefficiencyofafloatingowcpentagonalbackwardbentductbuoywaveenergyconverter
期刊论文
OAI收割
中国海洋工程英文版, 2019, 卷号: 033, 期号: 003, 页码: 297
作者:
LI Meng
;
WU Rukang
;
WU Bijun
;
ZHANG Yunqiu
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/11/30
BBDB wave energy conversion technology and perspective in China
期刊论文
OAI收割
OCEAN ENGINEERING, 2018, 卷号: 169, 页码: 281-291
作者:
Wu, Bijun
;
Li, Meng
;
Wu, Rukang
;
Chen, Tianxiang
;
Zhang, Yunqiu
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/10/29
Wave energy
Backward bent duct buoy (BBDB)
Capture width ratio (CWR)
Wave-to-wire conversion efficiency
Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors
期刊论文
OAI收割
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 281-294
作者:
Xing, Jing
;
Zhang, Rukang
;
Jiang, Xiangrui
;
Hu, Tianwen
;
Wang, Xinjun
  |  
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2019/01/08
Identification of novel inhibitors of histone acetyltransferase hMOF through high throughput screening
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 867-876
作者:
Zhang, Rukang
;
Wang, Jiang
;
Zhao, Liang
;
Liu, Shien
;
Du, Daohai
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
High throughput screening
Epigenetics
Histone acetyltransferase
MOF
Inhibitor
Computer-Aided Drug Design in Epigenetics
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2018, 卷号: 6
作者:
Lu, Wenchao
;
Zhang, Rukang
;
Jiang, Hao
;
Zhang, Huimin
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
drug discovery
epigenetics
small-molecule inhibitor
computer-aided drug design
virtual screening