中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
沈阳自动化研究所 [3]
采集方式
OAI收割 [7]
内容类型
期刊论文 [6]
会议论文 [1]
发表日期
2023 [1]
2022 [3]
2021 [1]
2015 [1]
2010 [1]
学科主题
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Sequence-based drug design as a concept in computational drug design
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21
作者:
Chen, Lifan
;
Fan, Zisheng
;
Chang, Jie
;
Yang, Ruirui
;
Hou, Hui
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2023/10/17
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 19
作者:
Hu, Cheng-Long
;
Chen, Bing-Yi
;
Li, Zijuan
;
Yang, Tianbiao
;
Xu, Chun-Hui
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/12/13
Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 1, 页码: 103-119
作者:
Tan, Xiaoqin
;
Li, Chunpu
;
Yang, Ruirui
;
Zhao, Sen
;
Li, Fei
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/06/15
Optogenetically engineered cell-based graphene transistor for pharmacodynamic evaluation of anticancer drugs
期刊论文
OAI收割
Sensors and Actuators B: Chemical, 2022, 卷号: 358, 页码: 1-11
作者:
Yang J(杨佳)
;
Li GX(李恭新)
;
Zu LP(祖立鹏)
;
Wang WX(王文学)
;
Ge ZX(葛治星)
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2022/03/07
Cell-based biosensor
Optogenetics
Photosensitive proteins
Cancer cells
Graphene transistor
Pharmacodynamic evaluation
Drug target inference by mining transcriptional data using a novel graph convolutional network framework
期刊论文
OAI收割
PROTEIN & CELL, 2021, 页码: 21
作者:
Zhong, Feisheng
;
Wu, Xiaolong
;
Yang, Ruirui
;
Li, Xutong
;
Wang, Dingyan
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/12/01
drug target inference
transcriptomics
deep learning
experimental verification
Determination of Base Binding Strength and Base Stacking Interaction of DNA Duplex Using Atomic Force Microscope
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2015, 卷号: 5, 页码: 1-7
作者:
Zhang, Tianbiao
;
Zhang CL(张常麟)
;
Dong ZL(董再励)
;
Guan, Yifu
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2015/07/05
Measurement of interchain binding affinity of nucleic acid duplex using atomic force microscopy
会议论文
OAI收割
4th IEEE International Conference on Nano/Molecular Medicine and Engineering, IEEE NANOMED 2010, Hong Kong/Macau, China, December 5-9, 2010
作者:
Zhang, Tianbiao
;
Zhang CL(张常麟)
;
Dong ZL(董再励)
;
Guan, Yifu
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2013/04/21
Atomic force microscopy
Binding energy
Cluster analysis
DNA
Experiments
Hydrogen
Precision engineering
Sodium
Sodium chloride