机构

• 上海药物研究所 [14]
• 南京地质古生物研究所 [1]

采集方式

• OAI收割 [15]

内容类型

• 期刊论文 [15]

发表日期

• 2025 [2]
• 2024 [7]
• 2023 [2]
• 2022 [2]
• 2021 [1]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共15条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择作者升序作者降序发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序 Characterization of the specific proteins to which HH-A, a drug that alleviates ischemic brain injury, binds in rat plasma 期刊论文  OAI收割 DRUG METABOLISM AND DISPOSITION, 2025, 卷号: 53, 期号: 7, 页码: 15 作者:  Zhao, Jie;  Zheng, Yuandong;  Lei, Peng;  Zhang, Yuying;  Zhang, Pingping   |  收藏  |  浏览/下载：16/0  |  提交时间：2025/08/20 Stroke  Covalent binding  HH-A  Ischemic brain injury  Proteomics   Characterization of preclinical radio ADME properties of ARV-471 for predicting human PK using PBPK modeling 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL ANALYSIS, 2025, 卷号: 15, 期号: 5, 页码: 15 作者:  He, Yifei;  Zhu, Chenggu;  Lei, Peng;  Yang, Chen;  Zhang, Yifan   |  收藏  |  浏览/下载：12/0  |  提交时间：2025/08/20 PROTAC  Vepdegestrant (ARV-471)  Radiolabeling  In vitro-in vivo extrapolation (IVIVE)  Physiologically based pharmacokinetic  (PBPK) model   Utility of quantitative whole-body autoradiography (QWBA) and oxidative combustion (OC) analysis in the assessment of tissue distribution of [14C]Mefuparib (CVL218) in SD and LE rats 期刊论文  OAI收割 PLOS ONE, 2024, 卷号: 19, 期号: 12, 页码: 13 作者:  Li, Xinmei;  Wang, Feiyu;  Zhang, Xinyue;  Shen, Xiaokun;  Yang, Chunhao   |  收藏  |  浏览/下载：27/0  |  提交时间：2025/04/01 Radioactive ADME Demonstrates ARV-110's High Druggability Despite Low Oral Bioavailability 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 15 作者:  He, Yifei;  Zheng, Yuandong;  Zhu, Chenggu;  Lei, Peng;  Yu, Jinghua   |  收藏  |  浏览/下载：52/0  |  提交时间：2024/09/26 Application of Electro-Activated Dissociation Fragmentation Technique to Identifying Glucuronidation and Oxidative Metabolism Sites of Vepdegestrant by Liquid Chromatography-High Resolution Mass Spectrometry 期刊论文  OAI收割 DRUG METABOLISM AND DISPOSITION, 2024, 卷号: 52, 期号: 7, 页码: 634-643 作者:  He, Yifei;  Hou, Pengyi;  Long, Zhimin;  Zheng, Yuandong;  Tang, Chongzhuang   |  收藏  |  浏览/下载：26/0  |  提交时间：2024/11/26 Absorption, distribution, metabolism and excretion of linaprazan glurate in rats 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 242, 页码: 10 作者:  Zhang, Xinyue;  Liu, Donghui;  Lu, Ming   |  收藏  |  浏览/下载：60/0  |  提交时间：2024/05/07 Linaprazan glurate  [14C]linaprazan glurate  Linaprazan  ADME  Radio-labeling  P-CAB   Pharmacokinetics and metabolite identification of 23-hydroxybetulinic acid in rats by using liquid chromatography-mass spectrometry method 期刊论文  OAI收割 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 10 作者:  Xue, Mingzhen;  Yang, Cheng;  Huang, Wensi;  He, Yifei;  Yang, Chen   |  收藏  |  浏览/下载：75/0  |  提交时间：2024/05/22 23-hydroxybetulinic acid  Pharmacokinetics  Metabolism  UPLC-MS  LC-MS/MS   Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11 作者:  Wang, Weiqiang;  Chen, Chong;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong   |  收藏  |  浏览/下载：94/0  |  提交时间：2024/01/16 LN005  Metabolism  Peptide -drug conjugates  UHPLC-HRMS  Doxorubicin   Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS 期刊论文  OAI收割 XENOBIOTICA, 2024, 页码: 9 作者:  Yuan, Yali;  Wang, Weiqiang;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong   |  收藏  |  浏览/下载：61/0  |  提交时间：2024/02/19 peptide-drug conjugate  PDC  LN005  metabolite identification  liver S9s   Absorption, Distribution, Metabolism, and Excretion of [14C]BS1801, a Selenium-Containing Drug Candidate, in Rats 期刊论文  OAI收割 MOLECULES, 2023, 卷号: 28, 期号: 24, 页码: 16 作者:  Yang, Cheng;  Xue, Mingzhen;  He, Yifei;  Yin, Hanwei;  Yang, Chen   |  收藏  |  浏览/下载：42/0  |  提交时间：2024/01/26 [C-14]BS1801  BS1801 (butaselen)  tissue distribution  metabolism  mass balance  selenium