中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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期刊论文 [289]
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Cell Biolo... [4]
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Predicting Food-Drug Interactions between Piperine and CYP3A4 Substrate Drugs Using PBPK Modeling
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 卷号: 25, 期号: 20, 页码: 13
作者:
Lin, Feifei
;
Hu, Yingchun
;
Zhang, Yifan
;
Zhao, Lijuan
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/11/26
PBPK modeling
piperine
food-drug interaction
Safety, tolerability and pharmacokinetics of forsythin in healthy subjects: a double-blinded, placebo-controlled single-dose and multiple-dose escalation and food effect study
期刊论文
OAI收割
ANNALS OF MEDICINE, 2023, 卷号: 55, 期号: 2, 页码: 9
作者:
Li, Cuiyun
;
Wu, Min
;
Zhang, Hong
;
Zhu, Xiaoxue
;
Fu, Li
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2024/01/16
Forsythin
pharmacokinetics
safety
tolerability
food effect
Absorption, Distribution, Metabolism, and Excretion of [
14
C]BS1801, a Selenium-Containing Drug Candidate, in Rats
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 24, 页码: 16
作者:
Yang, Cheng
;
Xue, Mingzhen
;
He, Yifei
;
Yin, Hanwei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/01/26
[C-14]BS1801
BS1801 (butaselen)
tissue distribution
metabolism
mass balance
selenium
Conference report for the 10th China Bioanalysis Forum annual meeting
期刊论文
OAI收割
BIOANALYSIS, 2023, 页码: 4
作者:
Dong, Kelly
;
Zhu, Mingshe
;
Tang, Daniel
;
Jin, Fan
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/12/19
China Bioanalysis Forum
CBF
ICH M10
DMPK and Bioanalysis for New Modalities
A validated LC-MS/MS method for the quantification of bevacizumab in rat, cynomolgus monkey, and human serum
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 11
作者:
Zhou, Ainan
;
Yu, Jinghua
;
Wu, Yali
;
Xue, Hao
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
Monoclonal antibody
Bevacizumab
LC-MS
MS
Surrogate peptide
Pharmacokinetics
Serum
Pharmacokinetics, Mass Balance, Tissue Distribution, and Metabolism of [
3
H]Catalpol in Rats: the Main Bioactive Component of
Rehmannia glutinosa
for the Treatment of Ischemic Stroke
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2023, 页码: 10
作者:
Ge, Xinyu
;
Zheng, Yuandong
;
He, Yifei
;
Chen, Chong
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/12/08
[H-3]catalpol
Rehmannia glutinosa
mass balance
tissue distribution
metabolism
intestinal flora
ischemic stroke.
Simultaneous quantification of 3 ',4 '-dimethoxy flavonol-3-O-glucoside and its major metabolite in human plasma by LC-MS/MS and its application to a clinical pharmacokinetic study
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 225, 页码: 9
作者:
Wang, Lu
;
Shen, Haifeng
;
Zhan, Yan
;
Zhang, Yifan
;
Zhang, Yong
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2023/04/10
3?4?-Dimethoxy flavonol-3-O-glucoside
Aglycone glucuronide
LC-MS
MS
Human pharmacokinetic study
Covalent Binding Mechanism of Furmonertinib and Osimertinib With Human Serum AlbuminS
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2023, 卷号: 51, 期号: 1, 页码: 8-16
作者:
Wu, Yali
;
Chen, Lili
;
Chen, Jian
;
Xue, Hao
;
He, Qingfeng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/27
Mechanistic Study on the Species Differences in Excretion Pathway of HR011303 in Humans and Rats
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 809-818
作者:
Guo, Zitao
;
Liu, Mengling
;
Meng, Jian
;
Xue, Yaru
;
Huang, Qi
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/08/16
Pharmacokinetics, Mass Balance, and Metabolism of the Novel Urate Transporter 1 Inhibitor [14C]HR011303 in Humans: Metabolism Is Mediated Predominantly by UDP-Glucuronosyltransferase
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 798-808
作者:
Zheng, Yuandong
;
Zhang, Hua
;
Liu, Mengling
;
Li, Guangze
;
Ma, Sheng
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/08/16