中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10
作者:
Zhang, Chun
;
Yan, Xue
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Cao, Qing
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Imidazo[2,1-b][1,3,4]thiadiazole
Inhibitory activities
Fluorescence imaging
Zebrafish
SHP2
EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1
作者:
Jiang, Shuai-Qing
;
Xu, Dong
;
Hoof, Agnes P. C. van
;
Lei, Wei-Hua
;
Liu, Yuan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/07/28
Metabolomic and evolutionary integration unveils medicinal potential in six
Corydalis
species
期刊论文
OAI收割
MOLECULAR HORTICULTURE, 2025, 卷号: 5, 期号: 1, 页码: 14
作者:
Gao, Yun
;
Zhou, Xiangyu
;
Yan, Mengxiao
;
Wang, Zhengwei
;
Zhong, Xin
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/08/20
Corydalis
genus
Benzylisoquinoline alkaloids (BIAs)
Evolutionary analysis
Metabolomics
Medicinal resources
Nonlinear Imaging Detection of Organ Fibrosis in Minute Samples for Early Stage Utilizing Dual-Channel Two-Photon and Second-Harmonic Excitation
期刊论文
OAI收割
BIOSENSORS-BASEL, 2025, 卷号: 15, 期号: 6, 页码: 16
作者:
Yu, Bo-Song
;
Cheng, Qing-Di
;
Liu, Yi-Zhou
;
Zhang, Rui
;
Li, Da-Wei
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
nonlinear imaging
two-photon excitation
second harmonic generation
fibrosis
Species difference in the excretion routes of Ciprofol (HSK3486) in rats and humans: Contribution of hepatic transporters and renal UDP-glucuronosyltransferase enzymes
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2025, 卷号: 53, 期号: 6, 页码: 10
作者:
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/08/20
Excretion
Glucuronide metabolites
Multidrug resistance protein
Species differences
UGT enzymes
Exploring Origin-Dependent Susceptibility of Smooth Muscle Cells to Aortic Diseases Through Intersectional Genetics
期刊论文
OAI收割
CIRCULATION, 2025, 卷号: 151, 期号: 17, 页码: 1248-1267
作者:
Han, Ximeng
;
Li, Yi
;
Wang, Enci
;
Zhu, Huan
;
Huang, Xiuzhen
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/06/23
aortic diseases
developmental origin
lineage tracing
smooth muscle cell
TGF-beta
Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
Identification of CDKN1A as a potential key risk factor in MASLD progression
期刊论文
OAI收割
FASEB JOURNAL, 2025, 卷号: 39, 期号: 7, 页码: 15
作者:
Deng, Lijuan
;
Deng, Jianxin
;
Luo, Liping
;
Yang, Hongjia
;
Sun, Mengxue
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/05/27
biomarkers
CDKN1A
liver
MASLD
RNA-seq
Oral FPR2/ALX modulators tune myeloid cell activity to ameliorate mucosal inflammation in inflammatory bowel disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Yang, Wen-sheng
;
Liu, Qing
;
Li, Yang
;
Li, Guan-yi
;
Lin, Shi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/04/24
IBD
FPR2/ALX
Quin-C1
Quin-C7
neutrophils
macrophages
A unified protocol for the synthesis of chromones, thiochromones and γ-pyrones
via
a dehydrative rearrangement reaction at room temperature
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2025, 页码: 9
作者:
Wang, Yue-Qi
;
Jin, Wei-Li
;
Chen, Hui-Qing
;
Zhou, Jin-Xin
;
Shen, Hong-Yan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/05/27