中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [46]
上海生物化学与细胞生... [1]
上海营养与健康研究所 [1]
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OAI收割 [48]
内容类型
期刊论文 [48]
发表日期
2025 [1]
2024 [11]
2023 [6]
2022 [8]
2021 [13]
2020 [2]
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学科主题
Cell Biolo... [1]
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Weight Loss Blockbuster Development: A Role for Unimolecular Polypharmacology
期刊论文
OAI收割
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2025, 卷号: 65, 页码: 191-213
作者:
Zhou, Qingtong
;
Li, Guanyi
;
Hang, Kaini
;
Li, Jie
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/04/01
overweight
glucagon-like peptide-1 receptor
unimolecular
polypharmacology
tirzepatide
retatrutide
metabolic diseases
Molecular basis of enhanced GLP-1 signaling mediated by GLP-1(9-36) in conjunction with LSN3318839
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 5069-5073
作者:
Li, Jie
;
Li, Guanyi
;
Mai, Yiting
;
Liu, Xiao
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/01/06
GLP-1(9-36)
Cryo-electron microscopy
Metabolite
Allosteric modulation
Single-cell mapping of peripheral blood mononuclear cells reveals key transcriptomic changes favoring coronary artery lesion in IVIG-resistant Kawasaki disease
期刊论文
OAI收割
HELIYON, 2024, 卷号: 10, 期号: 18, 页码: 15
作者:
Zheng, Yuanzheng
;
Zhou, Yan
;
Zhu, Di
;
Fu, Xing
;
Xie, Cao
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/10/21
Kawasaki disease
IVIG-Resistant
Single cell RNA-Sequencing
Coronary artery lesion
Single-cell sequencing reveals the heterogeneity of pancreatic neuroendocrine tumors under genomic instability and histological grading
期刊论文
OAI收割
ISCIENCE, 2024, 卷号: 27, 期号: 9, 页码: 18
作者:
Ye, Zeng
;
Zhou, Yan
;
Hu, Yuheng
;
Li, Qiang
;
Xu, Zijin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/11/05
tumor cells
CNV neutral tumor cells
neuroendocrine cells
profile
Absence of PNET formation and normal longevity in a mouse model of Mahvash disease
期刊论文
OAI收割
HELIYON, 2024, 卷号: 10, 期号: 15, 页码: 13
作者:
Xu, Yingna
;
Liu, Qiaofeng
;
Chen, Chuan-Wei
;
Wang, Qiuying
;
Du, Tianyuan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/09/26
Glucagon
Glucagon receptor
Amino acid
Metabolism
Mahvash disease
Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 4
作者:
Li, Wenzhuo
;
Zhou, Qingtong
;
Cong, Zhaotong
;
Yuan, Qingning
;
Li, Wenxin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/22
Structural Mass Spectrometry Captures Residue-Resolved Comprehensive Conformational Rearrangements of a G Protein-Coupled Receptor
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 卷号: 146, 期号: 29, 页码: 20045-20058
作者:
Liu, Hongyue
;
Yan, Pengfei
;
Zhang, Zhaoyu
;
Han, Hongbo
;
Zhou, Qingtong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/09/26
A homotrimeric GPCR architecture of the human cytomegalovirus revealed by cryo-EM
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 4
作者:
Chen, Yanyan
;
Li, Yang
;
Zhou, Qingtong
;
Cong, Zhaotong
;
Lin, Shi
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/06/27
Distinct roles of the extracellular surface residues of glucagon-like peptide-1 receptor in B-arrestin 1/2 signaling
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2024, 卷号: 968, 页码: 17
作者:
Lei, Saifei
;
Meng, Qian
;
Liu, Yanyun
;
Liu, Qiaofeng
;
Dai, Antao
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/05/22
GLP-1R
B-arrestin 1/2
Biased agonism
Bioluminescence resonance energy transfer
Proteomics profiling
High expression of GPR160 in prostate cancer is unrelated to CARTp-mediated signaling pathways
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 3, 页码: 1467-1471
作者:
Ye, Chenyu
;
Zhou, Qingtong
;
Lin, Shi
;
Yang, Wensheng
;
Cai, Xiaoqing
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/05/22
GPR160
CARTp
Prostate cancer
Signaling pathway