中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
地球化学研究所 [3]
海洋研究所 [3]
地理科学与资源研究所 [1]
计算技术研究所 [1]
国家天文台 [1]
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采集方式
OAI收割 [19]
内容类型
期刊论文 [19]
发表日期
2024 [2]
2023 [2]
2022 [3]
2021 [2]
2020 [2]
2016 [5]
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学科主题
环境地球化学 [2]
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Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 17, 页码: 15220-15245
作者:
Saidahmatov, Abdusaid
;
Li, Jianan
;
Xu, Shihao
;
Hu, Xiaobei
;
Gao, Xiangqian
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/10/21
Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/05/07
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
Construction of Diversified Penta-Spiro-Heterocyclic and Fused-Heterocyclic Frameworks with Potent Antitumor Activity
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2023, 页码: 7
作者:
Liu, Qi
;
Liu, Xuyi
;
Li, Yazhou
;
Zhou, Yu
;
Zhao, Linxiang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
spiro
fused-heterocyclic frameworks
substrate- and pH- controlled strategies
C-H activation
[4+1] and [4+2] annulation
antitumor
indazolone
Discovery of Novel Imidazo[4,5-c]quinoline Derivatives to Treat Inflammatory Bowel Disease (IBD) by Inhibiting Multiple Proinflammatory Signaling Pathways and Restoring Intestinal Homeostasis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21
作者:
Liang, Xuewu
;
Xie, Yongle
;
Liu, Xuyi
;
Xu, Hui
;
Ren, Hairu
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/11/11
Effectiveness of the Qilian Mountain Nature Reserve of China in Reducing Human Impacts
期刊论文
OAI收割
LAND, 2022, 卷号: 11, 期号: 7, 页码: 12
作者:
Li, Shicheng
;
Su, Shan
;
Liu, Yanxia
;
Zhou, Xuewu
;
Luo, Quanxin
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/09/21
human impacts
protected areas
evaluation
Qilian Mountain
road distribution
night light
land use
population density
Discovery of Novel Pyrrolo[2,3-d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 2, 页码: 1243-1264
作者:
Liang, Xuewu
;
Tang, Shuai
;
Liu, Xuyi
;
Liu, Yingluo
;
Xu, Qifu
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2022/06/15
I-2-induced cascade cyclization and dearomatization of indoles for the highly efficient synthesis of iodinated and vinylic spiroindolenines
期刊论文
OAI收割
GREEN CHEMISTRY, 2021, 卷号: 23, 期号: 22, 页码: 9165-9171
作者:
Wei, Xiaohui
;
Liang, Xuewu
;
Li, Yazhou
;
Liu, Qi
;
Liu, Xuyi
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/12/16
The Effects of Different Post-Heat Treatments on Rolling Contact Fatigue Behaviors of Direct Laser Cladding Inconel 625 Coatings
期刊论文
OAI收割
JOURNAL OF RENEWABLE MATERIALS, 2021, 卷号: 9, 期号: 1, 页码: 129-144
作者:
Zhang, Qiaoxin
;
Chen, Rui
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/04/12
Laser cladding
Inconel 625 coating
heat treatment
rolling contact fatigue
microstructure
One-step preparation of the superhydrophobic Al alloy surface with enhanced corrosion and wear resistance
期刊论文
OAI收割
MATERIALS AND CORROSION-WERKSTOFFE UND KORROSION, 2020, 页码: 8
作者:
Shi, Tian
;
Li, Xuewu
;
Zhang, Chuanwei
;
Wang, Hongxing
;
He, Zhenyan
  |  
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2021/04/12
Al alloy
corrosion resistance
electrochemical test
superhydrophobic behavior
wear resistance