机构

• 昆明植物研究所 [48]
• 上海药物研究所 [20]
• 青岛生物能源与过程研... [1]
• 生态环境研究中心 [1]

采集方式

• OAI收割 [70]

内容类型

• 期刊论文 [70]

发表日期

• 2025 [1]
• 2023 [6]
• 2022 [1]
• 2021 [11]
• 2020 [8]
• 2019 [8]
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学科主题

• Chemistry [4]
• Pharmacolo... [3]
• Biochemist... [2]
• Biophysics [1]
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• Life Scien... [1]
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筛选

浏览/检索结果: 共70条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis and activity evaluation of novel quinazolinone compounds as TRPC5 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 155, 页码: 20 作者:  Bai, Longhui;  Xiang, Yu;  Shen, Meiling;  Han, Yujun;  Li, Penghua   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/04/01 TRPC5  Inhibitors  Structural modifications and optimizing  Synthesis  Quinazolinone compounds  Activity evaluation   Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPAR alpha agonists by in silico studies and biochemical evaluation 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 16 作者:  Li, Yue;  Lv, Mengjia;  Shen, Meiling;  Gu, Xi;  Zhang, Li   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 NAFLD  PPAR alpha agonist  virtual screening  biochemical evaluation   Discovery of 2-(Methylcarbonylamino) thiazole as PDE4 inhibitors via virtual screening and biological evaluation 期刊论文  OAI收割 JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 124, 页码: 108567 作者:  Ma,Rui;  Song,Na;  Wang,Lveli;  Gu,Xi;  Xiong,Feng   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/07/22 PHOSPHODIESTERASE-4 INHIBITOR  ACCURATE DOCKING  APREMILAST  EFFICACY  INSIGHTS  DISEASE  ASTHMA  POTENT  GLIDE   Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 94, 页码: 117477 作者:  Shen,Meiling;  Li,Lingfeng;  Li,Yue;  Gu,Xi;  Bai,Longhui   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/07/22 TRPC5  Inhibitors  Virtual screening  Ca 2+channel  CHANNELS  IDENTIFICATION  PERMEABILITY  CALCIUM   Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493 作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/07/22 Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION   Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPARα agonists by in silico studies and biochemical evaluation 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 2256867 作者:  Li,Yue;  Lv,Mengjia;  Shen,Meiling;  Gu,Xi;  Zhang,Li   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/07/31 NAFLD  PPAR alpha agonist  virtual screening  biochemical evaluation  FATTY-ACID OXIDATION  GROMACS   Small-Molecule Drugs in Immunotherapy 期刊论文  OAI收割 MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359 作者:  Hao,Xuanrun;  Chen,Zhongliang;  Li,Haining;  Wei,Minqin;  Zuo,Zhili   |  收藏  |  浏览/下载：164/0  |  提交时间：2024/07/25 Cancer immunotherapy  inhibitors  Pd-1/Pd-L1 inhibitor  IDO inhibitor  STING agonists  ROR gamma t agonists  TGF  beta inhibitors  INDOLEAMINE 2,3-DIOXYGENASE  SIGNALING INHIBITOR  DENDRITIC CELLS  GROWTH  TUMOR  PATHWAY  PEMBROLIZUMAB  RECEPTORS  DISCOVERY  VADIMEZAN   Development and structure-activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors 期刊论文  OAI收割 NATURAL PRODUCTS AND BIOPROSPECTING, 2022, 卷号: 12, 期号: 6, 页码: 1 作者:  Deng Xu;  Huang Suling;  Ren Jian;  Pan Zhenghong;  Shen Yu   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/05/22 Metabolic syndrome  Tanshinones  Selective 11β-HSD1 inhibitors  Structure-activity relationships   Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 8 作者:  Guo, Sheng;  Xie, Hang;  Lei, Yu;  Liu, Bin;  Zhang, Li   |  收藏  |  浏览/下载：42/0  |  提交时间：2021/08/17 SARS-CoV-2  Main protease  Virtual screening  Biochemical evaluation   Heterogeneous Fenton-like reaction followed by GAC filtration improved removal efficiency of NOM and DBPs without adjusting pH 期刊论文  OAI收割 SEPARATION AND PURIFICATION TECHNOLOGY, 2021, 卷号: 260, 页码: - 作者:  Zhang, Yao;  Lu, Zhili;  Zhang, Zeyu;  Shi, Baoyou;  Hu, Chun   |  收藏  |  浏览/下载：12/0  |  提交时间：2021/12/23 Heterogeneous Fenton-like reaction  Granular activated carbon filtration  Natural organic matter  Disinfection by-products  Genotoxicity