中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [17]
近代物理研究所 [14]
合肥物质科学研究院 [11]
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期刊论文 [116]
会议论文 [3]
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Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10
作者:
Chen, Guofeng
;
Xie, Hang
;
Liu, Jiayuan
;
Shao, Qiang
;
Li, Minjun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Methyl substitution
Selectivity
FABP4 inhibitor
Anti-inflammation
Metabolic stability
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
;
Xiang, Huaijiang
;
Meng, Huyan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 317, 页码: 14
作者:
Chu, Hang
;
Zhang, Weitao
;
Tan, Yan
;
Diao, Zhipeng
;
Li, Peng
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Fibrosis
Inflammation
Lipogenesis
NASH
QZTGT
TMNP
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Jiang, Xiangrui
;
Su, Haixia
;
Shang, Weijuan
;
Zhou, Feng
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Neoproterozoic tectonic transition from subduction to back-arc extension along the western Yangtze Block, South China: Petrological evidence of Nb-enriched basalts and arc-type intrusive rocks
期刊论文
OAI收割
GONDWANA RESEARCH, 2023, 卷号: 122, 页码: 163-180
作者:
Zhu, Yu
;
Lai, Shao-Cong
;
Xie, Wan-li
;
Qin, Jiang-feng
;
Zhu, Ren-zhi
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/13
Nb-enriched basalt
Arc-type gabbros and diorites
Western Yangtze Block
Neoproterozoic
Subduction-related back-arc extension
Discovery of Polyphenolic Natural Products as SARS-CoV-2 Mpro Inhibitors for COVID-19
期刊论文
OAI收割
PHARMACEUTICALS, 2023, 卷号: 16, 期号: 2, 页码: 190
作者:
Kruger, Nadine
;
Kronenberger, Thales
;
Xie, Hang
;
Rocha, Cheila
;
Pohlmann, Stefan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
antivirals
coronavirus
COVID-19
covalent drugs
dynamic light scattering
inhibitors
main protease
natural products
Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 226, 页码: 780-792
作者:
Xiang, Yusen
;
Zhai, Guanglei
;
Li, Yaozong
;
Wang, Mengge
;
Chen, Xixiang
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
SARS-CoV-2
S-RBD
Ginkgolic acid
Environmental assessment of fabric wet processing from gate-to-gate perspective: Comparative study of weaving and materials
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 857, 页码: 11
作者:
Zhang, Siyuan
;
Xu, Chenye
;
Xie, Ruimin
;
Yu, Hang
;
Sun, Mingxing
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/01/30
Wet processing
Dyeing
Life Cycle Assessment
Textile cleaner production
Environmental assessment of fabric wet processing from gate-to-gate perspective: Comparative study of weaving and materials
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 857, 页码: 11
作者:
Zhang, Siyuan
;
Xu, Chenye
;
Xie, Ruimin
;
Yu, Hang
;
Sun, Mingxing
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/01/30
Wet processing
Dyeing
Life Cycle Assessment
Textile cleaner production
Flavonoids from the roots and rhizomes of Sophora tonkinensis and their in vitro anti-SARS-CoV-2 activity
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 1, 页码: 65
作者:
Li Zhuo
;
Xie Hang
;
Tang Chunping
;
Feng Lu
;
Ke Changqiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/05/22
Sophora tonkinensis
Flavonoid
Anti-SARS-CoV-2 activity
SARS-CoV-2 3CLpro
SARS-CoV-2 PLpro