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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [52]
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期刊论文 [127]
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Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10
作者:
Zhang, Chun
;
Yan, Xue
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Cao, Qing
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/08/20
Imidazo[2,1-b][1,3,4]thiadiazole
Inhibitory activities
Fluorescence imaging
Zebrafish
SHP2
Synthesis, fluorescence properties of novel thiazolo[3,2-b][1,2,4]triazol derivatives as potent SHP2 inhibitors and its uses in sensing for Fe3+and cell imaging
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1324, 页码: 12
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Gan, Su-Ya
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2025/01/14
Thiazolo[3,2-b][1,2,4]triazole
Salicylic acid
Fe3+ion
Fluorescence property
SHP2
Real-Time Estimation of BDS-3 Satellite Clock Offset with Ambiguity Resolution Using B1C/B2a Signals
期刊论文
OAI收割
REMOTE SENSING, 2024, 卷号: 16, 期号: 10, 页码: 16
作者:
Xie, Wei
;
Wang, Kan
;
Fu, Wenju
;
Xie, Shichao
;
Cui, Bobin
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2025/04/03
BDS-3
satellite clock offset estimation
AR
B1C/B2a
PPP-AR
Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16
作者:
Chen, Yun
;
Ning, Yi
;
Chen, Zhiwei
;
Xue, Yaping
;
Wu, Qingyun
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2023/10/17
Apoptosis
Diffuse large B-Cell lymphoma
Interleukin-1 receptor associated kinase 4
Structure-based drug design
2
3-Dihydrobenzofuran
Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9
作者:
Li, Hua-ying
;
Chen, Yi-li
;
Deng, Xiang-nan
;
Li, Huan-huan
;
Tan, Jie
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2023/10/17
cancer immunotherapy
B7-H3
PD-L1
bispecific antibodies
VHH
antibody-dependent cell-mediated cytotoxicity (ADCC)
Root-Extracted lignanamides from Limonium gmelinii (Willd.) Kuntze with a potential PTP1B inhibitory activity by regulating PI3K/AKT signaling pathway
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 9
作者:
Tuohongerbieke, Amanguli
;
Liu, Liu
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/10/17
Limonium gmelinii (Willd
) Kuntze
Plumbaginaceae
Lignanamides
Protein tyrosine phosphatase 1B inhibitors
PI3K
AKT Signaling Pathway
Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425
作者:
Sun, Yin
;
Tang, Haotian
;
Wang, Xiaoyan
;
Feng, Fang
;
Fan, Tiantian
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2022/08/16
TBK1 inhibitors
1H-pyrazolo[3
4-b]pyridine
structure-activity relationships (SARs)
immune response
cancer therapy
Modelling and Assessment of Single-Frequency PPP Time Transfer with BDS-3 B1I and B1C Observations
期刊论文
OAI收割
REMOTE SENSING, 2022, 卷号: 14, 期号: 5, 页码: 19
作者:
Wang, Shengli
;
Ge, Yulong
;
Meng, Xiaolin
;
Shen, Pengli
;
Wang, Kaidi
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/08/15
BDS-3
time transfer
single-frequency
B1I and B1C
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:
Yang, Xiao-Tong
;
Li, Tian-Ze
;
Geng, Chang-An
;
Liu, Pei
;
Chen, Ji-Jun
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol
alpha-glucosidase inhibitors
PTP1B inhibitors
Enzyme kinetics
TYROSINE-PHOSPHATASE 1B
DIABETES-MELLITUS
EPIDEMIOLOGY
Genome-wide analysis of the B3 transcription factors reveals that RcABI3/VP1 subfamily plays important roles in seed development and oil storage in castor bean (Ricinus communis)
期刊论文
OAI收割
PLANT DIVERSITY, 2022, 卷号: 44, 期号: 2, 页码: 201-212
作者:
Wang, Wen-Bo
;
Ao, Tao
;
Zhang, Yan-Yu
;
Wu, Di
;
Xu, Wei
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/04/30
B3 transcription factor
Castor bean
Gene expression
ABI3
VP1 subfamily
Seed development
Seed oil
EMBRYO DEVELOPMENT
LEAFY COTYLEDON2
ARABIDOPSIS RAV1
DOMAIN
MATURATION
PROTEIN
GENES
REGULATOR
SEQUENCE
GERMINATION