机构

• 上海药物研究所 [21]
• 长春应用化学研究所 [16]
• 西北高原生物研究所 [8]
• 大连化学物理研究所 [8]
• 昆明植物研究所 [6]
• 海洋研究所 [5]
• 更多

采集方式

• OAI收割 [91]
• iSwitch采集 [4]

内容类型

• 期刊论文 [92]
• 专利 [1]
• 会议论文 [1]
• 学位论文 [1]

发表日期

• 2025 [6]
• 2018 [2]
• 2017 [1]
• 2016 [3]
• 2015 [3]
• 2013 [3]
• 更多

学科主题

• Chemistry,... [3]
• Plant Scie... [3]
• 材料科学与物理化学 [3]
• 生物科学 [3]
• Chemistry [2]
• Pharmacolo... [2]
• 更多

筛选

浏览/检索结果: 共95条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 AI-enhanced virtual screening approach to hit identification for GluN1/GluN3A NMDA receptor 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12 作者:  Ji, Yue-shan;  Zeng, Yue;  Hu, Shao-fei;  Li, Shu-wang;  Zhang, Bei-chen   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/12/04 N-methyl-D-aspartate receptors (NMDARs)  GluN1/GluN3A  virtual screening  shape screening  rapid overlay of chemical structures (ROCS)  bidirectional and auto-regressive transformers (BART)   Identification of small-molecule inhibitors for GluN1/GluN3A NMDA receptors via a multiscale CNN-based prediction model 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9 作者:  Han, Li;  Zeng, Yue;  Qu, Zhi-yan;  Fang, Sui;  Wang, Hai-ying   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/12/04 N-methyl-D-aspartate receptors  GluN1/GluN3A  drug-target binding affinity  convolutional neural networks  ImageDTA  virtual screening   Discovery of selective GluN1/GluN3A NMDA receptor inhibitors using integrated AI and physics-based approaches 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 10 作者:  Li, Shi-wei;  Zeng, Yue;  Wu, Sa-nan;  Ma, Xin-yue;  Xu, Chao   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/09/09 N-methyl-D-aspartate receptors  GluN1/GluN3A  deep learning  molecular docking  virtual screening  binding site identification   Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 8 作者:  Wang, Shi-hang;  Zeng, Yue;  Yang, Hao;  Tian, Si-yuan;  Zhou, Yong-qi   |  收藏  |  浏览/下载：47/0  |  提交时间：2025/07/25 N-methyl-D-aspartate receptors  GluN1/GluN3A  ligand-based virtual screening  scaffold hopping  deep learning  GeminiMol   Dehydrotrametenolic acid methyl ester, a triterpenoid of Poria cocos, alleviates non-alcoholic steatohepatitis by suppressing NLRP3 inflammasome activation via targeting Caspase-1 in mice 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 17 作者:  Xia, Ling-yan;  Yu, Nai-rong;  Huang, Su-ling;  Qu, Hui;  Qin, Li   |  收藏  |  浏览/下载：44/0  |  提交时间：2025/06/23 non-alcoholic steatohepatitis  dehydrotrametenolic acid methyl ester  NLRP3 inflammasome  caspase-1  macrophage-hepatocyte/HSC crosstalk   An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9 作者:  Wang, Ze-chen;  Zeng, Yue;  Sun, Jin-yuan;  Chen, Xue-qin;  Wu, Hao-chen   |  收藏  |  浏览/下载：44/0  |  提交时间：2025/04/24 deep learning  scoring function  GluN1/GluN3A receptor  N-methyl-D-aspartate (NMDA) receptor  virtual screening  drug discovery   Precolumn derivatization LC-MS/MS method to simultaneous quantitation of 10 monosaccharides in rat plasma 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 234, 页码: 10 作者:  Li, Mengxue;  Li, Ping;  Ji, Yuting;  Tian, Yihua;  Zeng, Huiying   |  收藏  |  浏览/下载：101/0  |  提交时间：2023/10/17 LC-MS  MS  Monosaccharides  Derivatization  1-Phenyl-3-methyl-5-pyrazolone (PMP)  Biomarker   Engineering Corynebacterium glutamicum Mutants for 3-Methyl-1-butanol Production 期刊论文  OAI收割 BIOCHEMICAL GENETICS, 2019, 卷号: 57, 期号: 3, 页码: 443-454 作者:  Zhang, Yu;  Zhang, Xiaohuan;  Xiao, Shiyuan;  Qi, Wei;  Xu, Jingliang   |  收藏  |  浏览/下载：53/0  |  提交时间：2020/10/29 3-Methyl-1-butanol  L-Leucine  Corynebacterium glutanicum  Mutation breeding  Non-fermentation pathway   Vesicular glutamate transporter 1 (VGLUT1)-mediated glutamate release and membrane GluA1 activation is involved in the rapid antidepressant-like effects of scopolamine in mice 期刊论文  OAI收割 NEUROPHARMACOLOGY, 2018, 卷号: 131, 页码: 209-222 作者:  Yu, Hanjie;  Li, Mengmeng;  Zhou, Dongsheng;  Lv, Dan;  Liao, Qi   |  收藏  |  浏览/下载：111/0  |  提交时间：2019/01/08 Scopolamine  alpha-Amino-3-1-lydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)  Vesicular glutamate transporter 1 (VGLUT1)  Brain-derived neurotrophic factor (BDNF)  VGF (non-acronymic)  Bicaudal C homolog 1 gene (BICC1)   Vesicular glutamate transporter 1 (VGLUT1)-mediated glutamate release and membrane GluA1 activation is involved in the rapid antidepressant-like effects of scopolamine in mice 期刊论文  OAI收割 Neuropharmacology, 2018, 期号: 131, 页码: 209-222 作者:  Qi Liao;  Zhen Wang;  Dan Lv;  Dongsheng Zhou;  Mengmeng Li   |  收藏  |  浏览/下载：97/0  |  提交时间：2018/09/28 Scopolamine  a -amino-3-hydroxy-5-methyl-4-  Isoxazolepropionic Acid Receptor (Ampar)  Vesicular Glutamate Transporter 1 (Vglut1)  Brain-derived Neurotrophic Factor (Bdnf)  Vgf (Non-acronymic)  Bicaudal c Homolog 1 Gene (Bicc1)