机构

• 上海药物研究所 [4]
• 化学研究所 [1]
• 长春应用化学研究所 [1]

采集方式

• OAI收割 [6]

内容类型

• 期刊论文 [6]

发表日期

• 2024 [1]
• 2022 [1]
• 2016 [1]
• 2014 [1]
• 2012 [1]
• 2010 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共6条，第1-6条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3286-3290 作者:  Zheng, Miao;  Feng, Bo;  Zhang, Yumin;  Liu, Xin;  Zhao, Na   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/08/22 Non-covalent PLpro inhibitors  Antiviral activity  Structural-based drug design  Imidazo[4,5-b]pyridine scaffold   Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425 作者:  Sun, Yin   |  收藏  |  浏览/下载：54/0  |  提交时间：2022/08/16 TBK1 inhibitors  1H-pyrazolo[3  4-b]pyridine  structure-activity relationships (SARs)  immune response  cancer therapy   Design and synthesis of new potent PTP1B inhibitors with the skeleton of 2-substituted imino-3-substituted-5-heteroarylidene-1,3-thiazolidine-4-one: Part I 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 122, 页码: 756-769 作者:  Meng, Ge;  Zheng, Meilin;  Wang, Mei;  Tong, Jing;  Ge, Weijuan   |  收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 1,3-Thiazolidine-4-one  PTP1B  Pyrrole  Pyridine  Dock  SAR   Synthesis, characterization, and ethylene polymerization behaviors of late-transition metal complexes coordinated with chlorinated bis(arylimino)pyridine ligand 期刊论文  OAI收割 polymer, 2014, 卷号: 55, 期号: 18, 页码: 4611-4618 Liu, Heng; Wang, Feng; Liu, Li; Jai,Xiang-Yu; Zheng,Wenjie; Guo,Jun; Zhang,Chun-Yu; Bai,Chen-Xi; Hu,Yan-Ming; Zhang,Xue-Quan 收藏  |  浏览/下载：32/0  |  提交时间：2015/10/20 A series of late-transition metal complexes supported with chlorinated bis(arylimino)pyridine ligands [2  Ar = 2  Ar = 2  Ar = 2  Ar = 4-Cl-2  Ar = 4-Br-2  6-(ArN=CCl)(2)C5H3N]MtCl(2) (Ar = 2  6-(Pr2C6H3)-Pr-i  6-Et2C6H3  6-Me2C6H3  6-Me2C6H2  6-Me2C6H2  4  Mt = Fe (1b)  Mt = Co (1c)  Mt = Fe (1d)  Mt = Fe (1e)  Mt = Fe (1f)  6-Me3C6H2  Co (2b)  Ni (3c)  Co (2d)  Co (2e)  Co (2f)) were synthesized. At the presence of methylaluminoxane (MAO)  Mt = Fe (1a)  Fe(II)- and Co(II)- based complexes were highly active towards ethylene polymerization  Co (2a)  affording polymers with bimodal and unimodal molar. mass distributions  Ni (3a)  respectively  while the Ni(II)-based complexes gave no polymer products. Moreover  the obtained polyethylenes were predominately saturated and vinyl-terminated for Fe(II)- and Co(II)-based complexes  respectively. Changing the ligand environment  polymerization parameters also posed a great influence on the catalytic activities and the properties of the resulting polymers. (C) 2014 Elsevier Ltd. All rights reserved.   Synthesis and Characterization of a 2,4,6-Tri(2-thienyl)pyridine-Based Conjugated Polymer for OFET Applications 期刊论文  OAI收割 MACROMOLECULAR CHEMISTRY AND PHYSICS, 2012, 卷号: 213, 期号: 9, 页码: 917-923 作者:  Cao, Kangli;  Sun, Xiangnan;  Zhang, Qing;  Liu, Yunqi   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/04/09 Benzo[1  2-b:4  5-b']Dithiophene  Conjugated Polymers  Organic Field-effect Transistors  Stille Cross-coupling Reaction  Tri(2-thienyl)Pyridine   Discovery of novel (S)-alpha-phenyl-gamma-amino butanamide containing CCR5 antagonists via functionality inversion approach 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 卷号: 20, 期号: 7, 页码: 2219-2223 作者:  Zhang, Hu-Shan;  Feng, Dong-Zhi;  Chen, Li;  Long, Ya-Qiu   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 CCR5 antagonist  HIV-1 entry inhibitor  Functionality inversion  Bioisostere  Butanamide  Tropane  2-Methyl-3H-imidazo[4,5-b]pyridine  3H-[1,2,3]Triazolo[4,5-b]pyridine