中国科学院机构知识库网格系统: 检索

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	Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 247, 页码: 115034 作者: Song, Shukai; Tang, Haotian; Ran, Ting; Fang, Feng; Tong, Linjiang \| 收藏 \| 浏览/下载：1/0 \| 提交时间：2024/03/27 SyntaLinker Generative modelling TBK1 inhibitor pyrrolo[2 3-d]pyrimidine Structure-activity relationship
	Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study 期刊论文 OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425 作者: Sun, Yin; Tang, Haotian; Wang, Xiaoyan; Feng, Fang; Fan, Tiantian \| 收藏 \| 浏览/下载：36/0 \| 提交时间：2022/08/16 TBK1 inhibitors 1H-pyrazolo[3 4-b]pyridine structure-activity relationships (SARs) immune response cancer therapy
	TANK-binding kinase 1 (TBK1): An emerging therapeutic target for drug discovery 期刊论文 OAI收割 DRUG DISCOVERY TODAY, 2021, 卷号: 26, 期号: 10, 页码: 2445-2455 作者: Xiang, Shuang; Song, Shukai; Tang, Haotian; Smaill, Jeff B.; Wang, Aiqun \| 收藏 \| 浏览/下载：35/0 \| 提交时间：2021/12/01 Antibiotic resistance Computational biology Databases In silico tools
	Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway 期刊论文 OAI收割 ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298 作者: Ding, Chunyong; Song, Zilan; Shen, Ancheng; Chen, Tingting; Zhang, Ao \| 收藏 \| 浏览/下载：42/0 \| 提交时间：2021/05/24 Immunotherapy Anti-tumor cGAS STING TBK1 Small molecule modulators
	Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade 期刊论文 OAI收割 NATURE CELL BIOLOGY, 2017, 卷号: 19, 期号: 4, 页码: 362-+ 作者: Zhang, Qian; Meng, Fansen; Chen, Shasha; Wu, Shiying; Liu, Shengduo \| 收藏 \| 浏览/下载：14/0 \| 提交时间：2020/12/09 biomass breeding climate change crop yield decision support system