中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
合肥物质科学研究院 [4]
长春应用化学研究所 [1]
采集方式
OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2021 [1]
2019 [1]
2018 [1]
2016 [1]
2011 [1]
学科主题
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Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897
作者:
Lu, Tingting
;
Cao, Jiangyan
;
Zou, Fengming
;
Li, Xixiang
;
Wang, Aoli
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/04/26
BCR-ABL
ABL mutants
Chronic myeloid leukemia
Kinase inhibitor
Imatinib resistance
Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML)
期刊论文
OAI收割
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
作者:
Wu, Jiaxin
;
Wang, Aoli
;
Li, Xixiang
;
Chen, Cheng
;
Qi, Ziping
  |  
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2019/11/27
BCR-ABL
PDGFR
chronic myeloid leukemia
kinase inhibitor
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:
Liu, Xuesong
;
Wang, Beilei
;
Chen, Cheng
;
Jiang, Zongru
;
Hu, Chen
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/11
ABL kinase
Kinase inhibitor
ABL mutant
CML
Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML)
期刊论文
OAI收割
ONCOTARGET, 2016, 卷号: 7, 期号: 29, 页码: 45562-45574
作者:
Liu, Feiyang
;
Wang, Beilei
;
Wang, Qiang
;
Qi, Ziping
;
Chen, Cheng
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2017/11/21
Bcr-abl
Pdgfr
Chronic Myeloid Leukemia
Kinase Inhibitor
Small Interfering RNA for Effective Cancer Therapies
期刊论文
OAI收割
mini-reviews in medicinal chemistry, 2011, 卷号: 11, 期号: 2, 页码: 114-124
Wang X
;
Chen Y
;
Ren J
;
Qu X
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2012/06/11
HUMAN BREAST-CANCER
TELOMERASE REVERSE-TRANSCRIPTASE
NASOPHARYNGEAL CARCINOMA-CELLS
HUMAN HEPATOCELLULAR-CARCINOMA
ABL GENE-EXPRESSION
IN-VIVO DELIVERY
POLO-LIKE KINASE
WILD-TYPE P53
DOWN-REGULATION
COLORECTAL-CARCINOMA