中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [34]
上海生物化学与细胞... [23]
上海营养与健康研究... [19]
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合肥物质科学研究院 [10]
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OAI收割 [151]
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期刊论文 [151]
学位论文 [4]
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Oncology [18]
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Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14
作者:
Xu, Zhuo
;
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Zhu, Mengying
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Otilonium Bromide
Deubiquitinase
USP28
Selective inhibitor
LIM domain-containing protein Ajuba inhibits chemotherapy-induced apoptosis by negatively regulating p53 stability in colorectal cancer cells
期刊论文
OAI收割
MOLECULAR ONCOLOGY, 2023, 卷号: 17, 期号: 8, 页码: 1678-1691
作者:
Xu, Beihui
;
Li, Qi
;
Zhang, Jianjun
;
Chen, Fuxiang
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
Ajuba
apoptosis
chemoresistance
colorectal cancer
p53
Structure-based discovery of potent USP28 inhibitors derived from Vismodegib
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Zhou, Di
;
Xu, Zhuo
;
Huang, Yaodong
;
Wang, Hui
;
Zhu, Xiaoli
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
USP28
Structure-based
Vismodegib derivatives
Structure-activity relationships
c-Myc
Deep learning model based on contrast-enhanced ultrasound for predicting early recurrence after thermal ablation of colorectal cancer liver metastasis
期刊论文
OAI收割
EUROPEAN RADIOLOGY, 2022, 页码: 11
作者:
Zhao, Qin-xian
;
He, Xue-lei
;
Wang, Kun
;
Cheng, Zhi-gang
;
Han, Zhi-yu
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/03/20
Thermal ablation
Colorectal neoplasms
Ultrasound
Deep learning
Recurrence
BPTF inhibition antagonizes colorectal cancer progression by transcriptionally inactivating Cdc25A
期刊论文
OAI收割
REDOX BIOLOGY, 2022, 卷号: 55, 页码: 16
作者:
Guo, Ping
;
Zu, Shijia
;
Han, Shilong
;
Yu, Wendan
;
Xue, Guoqing
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/12/13
Colorectal cancer
BPTF
Cdc25A
c-Myc
Cell cycle
SPARCL1 exhibits different expressions in left- and right-sided colon cancer and is downregulated via DNA methylation
期刊论文
OAI收割
EPIGENOMICS, 2021
作者:
Hu, Hanguang
;
Wu, Dehao
;
Liu, Xibo
;
Yu, Haifeng
;
Xu, Junxi
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/11/01
DNA methylation
left-sided colon cancer
metastasis
right-sided colon cancer
SPARCL1
Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 3, 页码: 397-403
作者:
Li, Chunpu
;
Hu, Sha-Sha
;
Yang, Lisheng
;
Wang, Min
;
Long, Jian-Dong
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/05/24
SIRT1
inhibitor
structure-activity relationship
interaction
deacetylase
Second Primary Cancers After Kidney Cancers, and Kidney Cancers as Second Primary Cancers
期刊论文
OAI收割
EUROPEAN UROLOGY OPEN SCIENCE, 2021, 卷号: 24
作者:
Zheng, Guoqiao
;
Sundquist, Kristina
;
Sundquist, Jan
;
Chen, Tianhui
;
Foersti, Asta
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/03/15
Cancer incidence
Relative risk
Second primary cancer
Cancer etiology
Sex difference
Deep learning-based radiomics predicts response to chemotherapy in colorectal liver metastases
期刊论文
OAI收割
MEDICAL PHYSICS, 2020, 页码: 10
作者:
Wei, Jingwei
;
Cheng, Jin
;
Gu, Dongsheng
;
Chai, Fan
;
Hong, Nan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/01/06
colorectal liver metastases
chemotherapy
radiomics
contrast‐
enhanced multidetector computed tomography
deep learning
USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines
期刊论文
OAI收割
FEBS JOURNAL, 2020, 页码: 18
作者:
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Xiong, Muya
;
Zhu, Mengying
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/24
colorectal cancer
HDX-MS
inhibitor
USP25
USP28
Vismodegib