中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海神经科学研究所 [14]
上海药物研究所 [11]
长春应用化学研究所 [10]
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OAI收割 [44]
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期刊论文 [44]
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2024 [1]
2021 [2]
2019 [2]
2018 [3]
2017 [1]
2016 [3]
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Neuroscien... [6]
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Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 111, 页码: 16
作者:
Li, Xiaomei
;
Zhang, Hui
;
Dong, Sanfeng
;
Gao, Xuejie
;
Sun, Haiguo
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/09/26
Multiple myeloma
1-amido-2-one-4-thio-deoxypyranose
TRIP13 inhibitor
In vivo activity
In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues
期刊论文
OAI收割
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 卷号: 65, 期号: 2, 页码: 11
作者:
Uche, Fidelia Ijeoma
;
Guo, Xiaozhen
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
malaria
Plasmodium falciparum
Plasmodium berghei
bisbenzylisoquinoline alkaloids
cycleanine
metabolism
in vivo activity
antimalarial agents
drug metabolism
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
作者:
Gou,Leilei
;
Yue,Grace Gar-Lee
;
Puno,Pema Tenzin
;
Lau,Clara Bik-San
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/04/02
Breast cancer
Mast cell
Macrophage
Natural products
Herbs
Extracts
TUMOR-ASSOCIATED MACROPHAGES
NF-KAPPA-B
MEDIATED ALLERGIC REACTIONS
PRO-INFLAMMATORY CYTOKINES
ANTIINFLAMMATORY ACTIVITY
ATOPIC-DERMATITIS
UMBROSA ROOT
TNF-ALPHA
IN-VIVO
C-KIT
Graphene-based nanomaterials in biosystems
期刊论文
OAI收割
NANO RESEARCH, 2019, 卷号: 12, 期号: 2, 页码: 247—264
作者:
Lu, N
;
Wang, LQ
;
Lv, M
;
Tang, ZS
;
Fan, CH
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/12/30
CONTROLLED DRUG-RELEASE
DISPERSED TIO2 NANOCRYSTALS
IN-VIVO BIODISTRIBUTION
OXIDE NANOSHEETS
ANTIBACTERIAL ACTIVITY
SILVER NANOPARTICLES
GOLD NANOPARTICLES
NANO-GRAPHENE
QUANTUM DOTS
PATHOGENIC BACTERIA
trailbasedgenedeliveryandtherapeuticstrategies
期刊论文
OAI收割
actapharmacologicasinica, 2019, 卷号: 40, 期号: 11, 页码: 1373
作者:
Zhong Huihai
;
Wang Huiyuan
;
Li Jian
;
Huang Yongzhuo
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
APOPTOSIS-INDUCING LIGAND
MESENCHYMAL STEM-CELLS
PROSTATE-CANCER CELLS
DEATH RECEPTOR 5
CO-DELIVERY
IN-VIVO
MEDIATED APOPTOSIS
ANTITUMOR-ACTIVITY
TUMORICIDAL ACTIVITY
PROTEIN EXPRESSION
TRAIL
gene delivery
gene therapy
DNA
drug delivery systems
non-viral vectors
cancer therapy
Design, synthesis and biological evaluation of tetrahydronaphthyridine derivatives as bioavailable CDK4/6 inhibitors for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 140-153
作者:
Zha, Chuantao
;
Deng, Wenjia
;
Fu, Yan
;
Tang, Shuai
;
Lan, Xiaojing
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/01/08
Structure-based drug design
Selective CDK4/6 inhibitors
Structure-activity relationship study
In vivo antitumor activity
pH protective Y-1 receptor ligand functionalized antiphagocytosis BPLP-WPU micelles for enhanced tumor imaging and therapy with prolonged survival time
期刊论文
OAI收割
BIOMATERIALS, 2018, 卷号: 170, 页码: 70-81
作者:
Jiang, ZQ
;
Tian, YC
;
Shan, DY
;
Wang, YJ
;
Gerhard, E
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2018/09/06
Neuropeptide-y Analog
Drug-delivery
Breast-cancer
In-vivo
Photodynamic Therapy
Combination Therapy
Antitumor-activity
Sensitive Peptide
Anticancer Drug
Cellular Uptake
pH protective Y-1 receptor ligand functionalized antiphagocytosis BPLP-WPU micelles for enhanced tumor imaging and therapy with prolonged survival time
期刊论文
OAI收割
BIOMATERIALS, 2018, 卷号: 170, 页码: 70-81
作者:
Huang, Rong
;
Jiang, Zhenqi
;
Tian, Yuchen
;
Shan, Dingying
;
Wang, Yinjie
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2018/12/04
Neuropeptide-y Analog
Drug-delivery
Breast-cancer
In-vivo
Photodynamic Therapy
Combination Therapy
Antitumor-activity
Sensitive Peptide
Anticancer Drug
Cellular Uptake
Discovery of a class of diheteroaromatic amines as orally bioavailable CDK1/4/6 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5332-5336
作者:
Fu, Yan
;
Tang, Shuai
;
Su, Yi
;
Lan, Xiaojing
;
Ye, Yan
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Cyclin-dependent kinase
CDK inhibitor
Structure-activity relationship
In vitro and in vivo profiling
Simultaneous in vivo ascorbate and electrophysiological recordings in rat brain following ischemia/reperfusion
期刊论文
OAI收割
JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2016, 卷号: 781, 页码: 90-96
作者:
Cheng, Hanjun
;
Xiao, Tongfang
;
Wang, Dalei
;
Hao, Jie
;
Yu, Ping
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2018/01/10
In Vivo Electrochemistry
Integrated Dual-mode Microelectrode (Idmme)
Ascorbate
Single-unite Activity
Ischemia/reperfusion