机构

• 上海药物研究所 [4]
• 成都生物研究所 [1]
• 昆明植物研究所 [1]
• 近代物理研究所 [1]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2021 [2]
• 2016 [2]
• 2015 [1]
• 2009 [1]
• 2004 [1]

学科主题

• Pharmacolo... [1]
• Science & ... [1]

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2021, 卷号: 17, 期号: 12, 页码: 1238-1244 作者:  Liu, Qiufeng   |  收藏  |  浏览/下载：39/0  |  提交时间：2024/03/22 a Receptor  Structural Basis  Binding-site  Cck1 Receptor  Agonist  Activation  Mechanism  Optimization  Discovery  Rat   Insights into the molecular mechanism of positive cooperativity between partial agonist MK-8666 and full allosteric agonist AP8 of hGPR40 by Gaussian accelerated molecular dynamics (GaMD) simulations 期刊论文  OAI收割 COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 页码: 3978-3989 作者:  An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Liu, Huanxiang;  Yao, Xiaojun   |  收藏  |  浏览/下载：23/0  |  提交时间：2021/12/08 hGPR40  Positive binding cooperativity  Partial agonist  AgoPAM  Gaussian accelerated molecular dynamics simulation   Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文  OAI收割 DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286 作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin 收藏  |  浏览/下载：27/0  |  提交时间：2016/08/22 Alternative binding site  Bavachinin  Canonical ligand-binding pocket  Carbohydrate metabolism  Lipid metabolism  Pan-PPAR agonist  Synergistic effects   Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文  OAI收割 DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286 作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin   |  收藏  |  浏览/下载：72/0  |  提交时间：2019/01/08 Alternative binding site  Bavachinin  Canonical ligand-binding pocket  Carbohydrate metabolism  Lipid metabolism  Pan-PPAR agonist  Synergistic effects   Functional Impact of 14 Single Nucleotide Polymorphisms Causing Missense Mutations of Human alpha 7 Nicotinic Receptor 期刊论文  OAI收割 PLOS ONE, 2015, 卷号: 10, 期号: 9, 页码: - 作者:  Zhang, Qinhui;  Du, Yingjie;  Zhang, Jianliang;  Xu, Xiaojun;  Xue, Fenqin 收藏  |  浏览/下载：28/0  |  提交时间：2016/12/22 CHOLINERGIC ANTIINFLAMMATORY PATHWAY  POSITIVE ALLOSTERIC MODULATION  GATED ION-CHANNEL  ACETYLCHOLINE-RECEPTOR  AGONIST-BINDING  INTERNATIONAL UNION  TRANSMEMBRANE SITE  SILENT AGONIST  AMINO-ACIDS  ACTIVATION   A yeast two-hybrid technology-based system for the discovery of PPAR gamma agonist and antagonist 期刊论文  OAI收割 ANALYTICAL BIOCHEMISTRY, 2004, 卷号: 335, 期号: 2, 页码: 253-259 作者:  Chen, Q;  Chen, J;  Sun, T;  Shen, JH;  Shen, X   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 peroxisome pro liferato r-activated receptor gamma (PPAR gamma)  yeast two-hybrid  CREP-binding protein (CBP)  agonist  antagonist  alpha-galactosidase