中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
大连化学物理研究所 [8]
上海药物研究所 [6]
昆明植物研究所 [1]
采集方式
OAI收割 [15]
内容类型
期刊论文 [14]
会议论文 [1]
发表日期
2018 [1]
2017 [4]
2016 [3]
2015 [4]
2014 [1]
2013 [1]
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学科主题
物理化学 [1]
生物药物学 [1]
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Bavachinin analogues as agonists of pan-peroxisome proliferator-activated receptors
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2018, 卷号: 27, 期号: 7, 页码: 1851-1862
作者:
Yi, Jingyu
;
Du, Guoxin
;
Zhao, Yuanyuan
;
Zhang, Liuqiang
;
Li, Bo
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Bavachinin
Metabolic syndrome
PPARs
Reporter gene assaysThese authors contributed equally: Jingyu Yi, Guoxin Du
Rapid separation and simultaneous quantitative determination of 13 constituents in Psoraleae Fructus by a single marker using high-performance liquid chromatography with diode array detection
期刊论文
OAI收割
Journal of separation science, 2017, 卷号: 40, 期号: 21, 页码: 4191-4202
作者:
Zhang, Yimin
;
Chen, Zhiyong
;
Xu, Xiaokun
;
Zhou, Qiang
;
Liu, Xiaolong
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883
作者:
Yang, Ling
;
Ge, Guang-Bo
;
Jarvinen, Erkka
;
Troberg, Johanna
;
Finel, Moshe
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2017/12/20
UDP-glucuronosyltransferase
recombinant UGT1A10
intestine microsomes
intestinal glucuronidation
estradiol
estrone
morphine
SN-38
AMC
NCHN
bavachinin
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883
作者:
Troberg, Johanna
;
Jarvinen, Erkka
;
Ge, Guang-Bo
;
Yang, Ling
;
Finel, Moshe
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2017/12/20
UDP-glucuronosyltransferase
recombinant UGT1A10
intestine microsomes
intestinal glucuronidation
estradiol
estrone
morphine
SN-38
AMC
NCHN
bavachinin
Design, Synthesis, and Structure-Activity Relationships of Bavachinin Analogues as Peroxisome Proliferator-Activated Receptor Agonists
期刊论文
OAI收割
CHEMMEDCHEM, 2017, 卷号: 12, 期号: 2, 页码: 183-193
作者:
Du, Guoxin
;
Zhao, Yuanyuan
;
Feng, Li
;
Yang, Zhuo
;
Shi, Jiye
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
bavachinin
diabetes mellitus
PPAR
reporter gene assays
structure-activity relationships
Inhibition behavior of fructus psoraleae's ingredients towards human carboxylesterase 1 (hCES1)
期刊论文
OAI收割
XENOBIOTICA, 2016, 卷号: 46, 期号: 6, 页码: 503-510
作者:
Cao, Yun-Feng
;
Sun, Dong-Xue
;
Ge, Guang-Bo
;
Dong, Pei-Pei
;
Fu, Zhi-Wei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/06/20
Herb-drug Interaction
Toxicity
Human Carboxylesterase 1 (Ces1)
Fructus Psoraleae
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice
期刊论文
OAI收割
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:
Feng, Li
;
Luo, Huan
;
Xu, Zhijian
;
Yang, Zhuo
;
Du, Guoxin
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2016/08/22
Alternative binding site
Bavachinin
Canonical ligand-binding pocket
Carbohydrate metabolism
Lipid metabolism
Pan-PPAR agonist
Synergistic effects
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice
期刊论文
OAI收割
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:
Feng, Li
;
Luo, Huan
;
Xu, Zhijian
;
Yang, Zhuo
;
Du, Guoxin
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
Alternative binding site
Bavachinin
Canonical ligand-binding pocket
Carbohydrate metabolism
Lipid metabolism
Pan-PPAR agonist
Synergistic effects
Glucuronidation of bavachinin by human tissues and expressed UGT enzymes:Identification of UGT1A1 and UGT1A8 as the major contributing enzymes
期刊论文
OAI收割
drug metabolism and pharmacokinetics, 2015, 卷号: 30, 期号: 0, 页码: 358
作者:
Lv X(吕侠)
;
Jie Hou
;
Xia YL(夏杨柳)
;
Ning J(宁静)
;
He GY(何桂元)
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2016/11/24
Glucuronidation of bavachinin by human tissues and expressed UGT enzymes: Identification of UGT1A1 and UGT1A8 as the major contributing enzymes
期刊论文
OAI收割
drug metabolism and pharmacokinetics, 2015, 卷号: 30, 期号: 5, 页码: 358-365
作者:
Lv, Xia
;
Hou, Jie
;
Xia, Yang-Liu
;
Ning, Jing
;
He, Gui-Yuan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2015/11/17
Bavachinin
UDP-glucuronosyltransferases
UGT1A1
UGT1A8
Glucuronidation
Human tissues